Results 31 to 40 of about 7,022 (207)

Partial loss of function of the GHRH Receptor leads to mild Growth Hormone Deficiency [PDF]

, 2016
OBJECTIVE: Recessive mutations in GHRHR are associated with severe isolated growth hormone deficiency (IGHD), with a final height in untreated patients of 130 cm ± 10 cm (-7.2 ± 1.6 SDS; males) and 114 ± 0.7 cm (-8.3 ± 0.1 SDS; females).
Alatzoglou, K S, Dattani, M T, Gregory, L C, Hindmarsh, P C, Le Tissier, Paul, McCabe, M J, Romano, N, Saldanha, J W   +7 more
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Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency [PDF]

Annals of Pediatric Endocrinology & Metabolism
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy.
Chiara Rodaro, Gianluca Tamaro, Elena Faleschini, Gianluca Tornese   +3 more
doaj   +1 more source

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

Italian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni, S. Motta, N. Masera, S. Gasperini, A. Rovelli, R. Parini   +5 more
doaj   +1 more source

The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]

, 2016
Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea, Diaz, Graciela Susana, Recouvreux, Maria Victoria, Rifkin, Daniel B.   +3 more
core   +2 more sources

Role of cyclic AMP in the control of cell-specific gene expression [PDF]

, 1993
Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael, Nitsch, Doris, Schmid, Wolfgang, Schütz, Günther   +3 more
core   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes [PDF]

, 2013
The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models of ...
A Faivre-Bauman, A Rathinavelu, AB Abou-Samra, Abir Mukherjee, AF Gilkes, AH Tashjian Jr, AM Hamad, Andrew J. Lessey, Andrew Sunters, AR Yoder, Bigboy Simbi, CA McArdle, CA McArdle, CA McArdle, Caroline P. Wheeler-Jones, Craig A. McArdle, D Fan, D Müller, DJ Hartt, DM Dickey, FN Zeytin, G Rousseau, Gary F. Baxter, GY Koh, H Chusho, H Hao, I Kishimoto, Iain R. Thompson, Imelda M. McGonnell, IR Thompson, IR Thompson, J Horvath, KN Pandey, KN Pandey, Lorna Smith, LR Potter, LR Potter, LR Potter, LR Potter, LR Potter, LR Potter, LR Potter, LR Potter, MA Vieira, Mark S. Roberson, MB Henesy, MJ Lopez, N Tamura, PM Hinkle, RC Fowkes, RC Fowkes, RC Fowkes, RC Fowkes, Robert C. Fowkes, S Inagaki, S Suga, SA Bayol, Samantha M. Mirczuk, SE Abbey, SE Abbey-Hosch, SE Abbey-Hosch, SW John, T Sudoh, Victoria J. Lipscomb, Y Komatsu, Y Shimekake   +65 more
core   +4 more sources

Nonapeptide cell size differs between male morphs of the West African cichlid, Pelvicachromis pulcher

Journal of Fish Biology, EarlyView.
Abstract Alternative male morphs are found in many species of fishes. These morphs often differ in suites of social behaviours, such as aggression and territoriality, associated with alternative reproductive tactics. Such consistent morph‐typical behavioural profiles suggest common differences in underlying neuroendocrine mechanisms.
Adam R. Reddon, Douglas R. Wylie, Peter L. Hurd   +2 more
wiley   +1 more source

Basal encephalocele associated with morning glory syndrome: case report Encefalocele basal associada a síndrome "morning glory": relato de caso

Arquivos de Neuro-Psiquiatria, 2007
The basal encephaloceles refer to rare entities and they correspond to herniation of brain tissue through defects of skull along the cribiform plate or the sphenoid bone. A rare morning glory syndrome, with characteristic retinal defect has been reported
Ivanete Minotto, Nitamar Abdala, Adriana Aparecida Siviero Miachon, Angela Maria Spinola e Castro, Paulo Imamura, Roberto Gomes Nogueira   +5 more
doaj   +1 more source

Доповідь керівника міжнародної секції і Донецького відділення АЕН України академіка АЕН України [PDF]

, 2011
Pituitary dwarfism, associated with growth hormone deficiency, is an autosomal, recessively inherited disorder in shepherd dogs. Due to the serious nature of pituitary dwarfism and lack of efficient treatment, it is preferable to prevent dwarfs from ...
Макогон, Ю.В.
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