Results 41 to 50 of about 7,022 (207)

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]

open access: yes, 2017
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J   +6 more
core   +3 more sources

A Case of Congenital Hypothyroidism in Cats: Diagnostic Challenges and Therapeutic Outcomes

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Congenital hypothyroidism in a 3‐year‐old Persian cat was diagnosed via low total thyroxine levels unresponsive to TSH stimulation, alongside clinical signs of dwarfism and renal failure. Levothyroxine therapy significantly improved renal function and activity within 1 week.
Morteza Ezati Kakalar   +3 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Integrating Molt Migration Into Physiological Assessments of Inter‐Population Stress in a Globally Endangered Species

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
Feather corticosterone (fCORT) provides a powerful indicator of population‐level physiological responses to human disturbance, yet its interpretation is complicated by variation across taxa, habitats, and molt‐movement strategies. Using stable isotope analyses to account for molt migrants in the globally endangered Scaly‐sided Merganser (Mergus ...
Shurui Bai   +8 more
wiley   +1 more source

Relationship Between Gut Microbiota and Cancer Neuro‐Immunity

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
Tumour cells influence neural activity and microbiota homeostasis through cytokines and immune modulation. Meanwhile, gut microbiota regulates neural function through metabolic products, affects immune responses via neurotransmitters, feedback regulates neural activity and influences tumour microenvironment.
Danyang Wang   +7 more
wiley   +1 more source

Septo-optic dysplasia (case report)

open access: yesIndian Journal of Ophthalmology, 1991
Septo optic dysplasia is a rare developmental anomaly involving bilateral optic nerve hypoplasia, midline anomalies of the brain and hypothalamo-pituitary dysfunction.
Nayak Venkatesh, Bhat K
doaj  

The influence of pituitary volume on the growth response in growth hormone-treated children with growth hormone deficiency or idiopathic short stature [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism
Purpose Magnetic resonance imaging (MRI) can be used for assessing the morphology of the pituitary gland in children with short stature. The purposes of this study were: (1) to determine if pituitary volume (PV) can distinguish patients with growth ...
Jun Suk Oh   +6 more
doaj   +1 more source

Circulating Profiles of the Bile Acid Metabolomics in Patients With Polycystic Ovary Syndrome Treated With Metformin or Canagliflozin

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.
ABSTRACT Objective Bile acids are indispensable modulators in the development of polycystic ovary syndrome (PCOS). Our previous study identified that metformin and canagliflozin have similar efficacy in patients with PCOS combined with insulin resistance (IR).
Qi Yan   +8 more
wiley   +1 more source

Dwarfism in beef cattle and the influence of dwarfism genes on physiological response to hormone-induced stress [PDF]

open access: yes, 1961
This bulletin reports on Department of Animal Husbandry research project 198, 'Improvement of Beef Cattle Through Breeding'--P. [2].Digitized 2007 AES.Includes bibliographical references (pages 50-55)
Comfort, James E. (James Edwin), 1899-   +2 more
core  

PROP1 gene analysis in Portuguese patients with combined pituitary hormone deficiency [PDF]

open access: yes, 2006
OBJECTIVE: Mutations of the PROP1 gene lead to combined pituitary hormone deficiency (CPHD), which is characterized by a deficiency of GH, TSH, LH/FSH, PRL and, less frequently, ACTH.
Agapito, A   +12 more
core   +1 more source

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