Results 61 to 70 of about 25,996 (285)
Advanced Science, EarlyView.ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Ecology and EvolutionIsolated populations of Australian freshwater crocodiles (Crocodylus johnstoni) in few elevated, rocky escarpment areas of the Northern Territory of Australia reach sexual maturity earlier and generally have an adult size half that of their downstream ...
Katherine Brittain +8 more
doaj +1 more source
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
Thanatophoric Dwarfism ‐ A Delivery Dilemma
, 1977 Summary: A case of thanatophoric dwarfism, a fatal form of achondroplasia, is presented ...
Chang, A., Teoh, G., Morrison, J.
core +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Advanced Science, EarlyView.Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
Dwarfism in Disability Studies
This entry presents a broad overview of how dwarfism has been constructed in relation to various understandings of disability. With the advent of the social model of disability, dwarfism is a condition that should fit comfortably within Disability ...
Pritchard, Erin
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Dwarfism in ancient times: from worship to rejection [PDF]
, 2020 The objective of this paper is to outline some aspects of dwarfism in the Antiquity. The author focuses in particular on Ancient Egypt where one of the most prominent of gods – Bes – suffered from dwarfism. It was believed that little people were somehow
Grzesiak, Hanna
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Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides
Advanced Science, EarlyView.The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang +5 more
wiley +1 more source
Current insight into the molecular genetic basis of dwarfism in livestock [PDF]
, 2017 Impairment of bone growth at a young age leads to dwarfism in adulthood. Dwarfism can be categorised as either proportionate, an overall size reduction without changes in body proportions, or disproportionate, a size reduction in one or more limbs, with ...
dCSCA RMSC-1 +18 more
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Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source