Results 241 to 250 of about 572,821 (310)

Quantitative Muscle Magnetic Resonance Imaging Demonstrates Resolution of Muscle Edema in Refractory Dermatomyositis: A Post Hoc Analysis of a Proof‐of‐Concept Clinical Trial of Tofacitinib

open access: yesACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective To evaluate changes in muscle edema using short‐tau inversion recovery (STIR) imaging and quantitative diffusion‐weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping in patients with refractory dermatomyositis (DM) treated with tofacitinib. Methods This post hoc imaging analysis included patients from a 12‐week, open‐label
Mona Dabiri   +8 more
wiley   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1210-1223, May 2026.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito   +10 more
wiley   +1 more source

Macro Habitat‐Based T2‐Weighted MRI Radiomics and Deep Learning Fusion for Predicting Treatment Response and Prognosis After Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced rectal cancer (LARC) is highly heterogeneous. Reliable pretreatment prediction of tumor regression and prognosis remains an unmet clinical need to optimize personalized management.
Xiaoli Jin   +7 more
wiley   +1 more source

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