Results 51 to 60 of about 72,988 (243)

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Shape morphing of hydrogels by harnessing enzyme enabled mechanoresponse

Nature Communications
Hydrogels have been designed to react to many different stimuli which find broad applications in tissue engineering and soft robotics. However, polymer networks bearing mechano-responsiveness, especially those displaying on-demand self-stiffening and ...
Kuan Zhang, Yu Zhou, Junsheng Zhang, Qing Liu, Christina Hanenberg, Ahmed Mourran, Xin Wang, Xiang Gao, Yi Cao, Andreas Herrmann, Lifei Zheng   +10 more
doaj   +1 more source

Oxygen‐Inhibition Driven Compartmentalization of Dextran Microgels: Toward Fusible Colloidal Biomaterial Inks for 3D Printing

Advanced Materials, EarlyView.
Harnessing oxygen inhibition as a materials design principle enables the universal fabrication of core–shell microgels with tunable radial crosslinking gradients. This conceptually simple yet highly versatile strategy generates fusible colloidal bioinks that combine structural hierarchy with adaptive porosity.
Selin Bulut, Thomas Bissing, Tudor Lile, Hannah Küttner, Daniel Günther, Cédric Bergerbit, Dan Eugen Demco, Laura De Laporte, Andrij Pich   +8 more
wiley   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Role of Diagnostic Accuracy of Diffusion-Weighted Imaging In Adult Posterior Fossa Tumors – A Prospective Cross-Sectional Study

Journal of Pharmacy and Bioallied Sciences
Aim: This study aims to investigate the role of diffusion-weighted imaging (DWI) in enhancing the diagnostic accuracy of adult posterior fossa tumors.
B Keerthana, M Janani Moorthy, R Sarvesh, Vinoth Thangam   +3 more
doaj   +1 more source

A study on diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging in patients with prostate cancer [PDF]

Journal of Men's Health
Background: This study aims to evaluate the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), and their combination in prostate cancer patients.
Lili Ying, Kaiyan Hu, Haifeng Qiu, Lingling Ying   +3 more
doaj   +1 more source

Beban Kerja Mental dan Pendapatan dengan Kebahagiaan di Tempat Kerja Pada Dosen di Universitas Jember

Jurnal Ilmu Kesehatan Masyarakat, 2020
Kebahagiaan di tempat kerja adalah pola pikir seseorang untuk memaksimalkan potensi diri dan kinerja. Dosen yang mempunyai kebahagiaan di tempat kerja akan memiliki keterikatan yang tinggi dengan pekerjaannya, semangat, antusias, tekun dan berkonsentrasi
Dwi Sterida Mahani, Isa Ma'rufi, Reny Indrayani   +2 more
doaj   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source