Results 101 to 110 of about 1,539,393 (285)

Analysis of the Influence of Active Compounds Contained in Waste Bio-Fillers on the Biological Degradation Processes of Polylactide Compositions

Journal of Natural Fibers
Fruit pomace, used as bio-fillers for polymeric materials, possesses compounds including polyphenols, showing antimicrobial and antioxidant properties.
Malgorzata Latos-Brozio, Aleksandra Wdowiak, Wiktoria Kowalczyk, Dominik Dusza, Magdalena Efenberger-Szmechtyk, Małgorzata Piotrowska, Angelina Rosiak, Joanna Kałużna-Czaplińska, Anna Masek   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Elma Yapraklarından Elde Edilen Renkler ve Bu Renklerin Bazı Haslık Değerleri

Journal of Agricultural Sciences, 2000
Bu araşt ı rmada elma Starking Delicious çeş idi yapraklar ı doğal boyamada kullan ı lmışt ı r. Yün ipliğine göre % 100 oran ı nda elma yaprağı kullan ı larak mordans ı z ve ön mordanlama metodlan ile toplam 50 boyama yap ı lm ışt ı r.
Nuran Kayabaş, Filiz Ölmez
doaj   +1 more source

The Three Loop Isotopy and Framed Isotopy Invariants of Virtual Knots [PDF]

, 2013
This paper introduces two virtual knot theory ``analogues'' of a well-known family of invariants for knots in thickened surfaces: the Grishanov-Vassiliev finite-type invariants of order two.
A. Dye, Heather, Micah W. Chrisman
core  

Pressure-induced recovery of Fourier's law in one dimensional momentum-conserving systems

, 2016
We report the two typical models of normal heat conduction in one dimensional momentum-conserving systems. They show the Arrhenius and the non-Arrhenius temperature dependence.
Sato, Dye SK
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source