Results 231 to 240 of about 631,178 (293)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Marginal Fit, Internal Adaptation, and Microleakage of Preformed Metal Crowns: Impact of Three Preparation Techniques and Three Ion-Releasing Cements. [PDF]

Children (Basel)
Al-Haj Ali SN, Alsamaani H, Aldhilan S, Alodaib R.   +3 more
europepmc   +1 more source

Green-to-Red Photopolymerization via Dual-Role Dyes for Transparency-Tunable 3D-Printed Hydrogels. [PDF]

ACS Appl Polym Mater
Eftekhari A, Mattila A, Radmehr S, Santala V, Durandin N, Kellomäki M, Laaksonen T, Badria A.   +7 more
europepmc   +1 more source

Surface Modification of Gutta-Percha for the Use of Intact MTA as a Root Canal Sealer. [PDF]

J Funct Biomater
Sarilaksmi N, Nagano-Takebe F, Takahashi M, Kado T, Endo K, Nezu T.   +5 more
europepmc   +1 more source

Theoretical model and parameter optimization of embryo eggshell perforation under impact. [PDF]

Poult Sci
Wang X, Zhao M, Chen C, Chen H, Liang M, He C, Fu D, Zhu X, Sun H, Gao C.   +9 more
europepmc   +1 more source

A Multiscale Mechanistic Framework for Polydopamine Dyeing in Ultrablack Wool Textiles. [PDF]

Adv Sci (Weinh)
Jayamaha H, Siddharth K, Park K, Bressler M, Shepherd LM.   +4 more
europepmc   +1 more source

Substituent Effects of Heptamethine Cyanine Dyes on Drug Uptake in Patient-Derived Glioma Cells. [PDF]

ChemMedChem
Dumo CJ, Choi PJ, Liu Y, Muhammad O, Correia JA, Dragunow M, Park TI, Jose J.   +7 more
europepmc   +1 more source