Results 81 to 90 of about 631,178 (293)

High-sucrose diet inhibits basal secretion of intradentinal dye penetration-stimulating parotid hormone in pigs

open access: yes, 1994
Earlier studies indicated that feeding rats a high-sucrose diet for 1 wk decreases the intrinsic rate of intradentinal dye penetration in molar teeth. Because intradentinal dye penetration appears to be controlled by a parotid hormone, we investigated ...
J. M. Tieche, R. R. Steinman, J. Leonora
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Comparative evaluation of microleakage of glass ionomer and resin based fissure sealants, using noninvasive and invasive techniques

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2007
Introduction: Use of glass ionomer cement as pit and fissure sealant, has added benefit by its fluoride-releasing property. The efficacy of using invasive and non-invasive techniques was assessed by microleakage of Glass ionomer (Triage, G C Corporation,
SH Javadinejad, SM Razavi, S Dehghani
doaj  

APICAL MICROLEAKAGE OF VARIOUS BIOMATERIALS IN SIMULATED IMMATURE APICES

open access: yesSelcuk Dental Journal, 2019
Background:: In the treatment of open apex teeth, one-step apexification has been reported as an alternative method to the use of long-term calcium hydroxide. Methods:The present study evaluated and compared apical microleakage when ProRoot MTA (Dentsply)
Fatih Tulumbacı   +3 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Comparison of coronal sealing of flowable composite, resin-modified glass ionomer, and mineral trioxide aggregate in endodontically treated teeth: An in-vitro study

open access: yesDental Research Journal
Background: Coronal seal is one of the essential factors that affects the success of endodontic treatment and reinforces the apical seal. The intra-orifice barrier is an efficient alternative approach to decrease coronal leakage in endodontically treated
Mahla Tavakoli   +3 more
doaj   +1 more source

Assessment of coronal leakage of a new temporary light-curing filling material in endodontically treated teeth

open access: yesIndian Journal of Dental Research, 2014
Introduction: The aim of this study was to evaluate the sealing ability of a new temporary filling material X-Temp LC (DFL, São Paulo, SP, Brazil) compared with that obtained for Coltosol (Vigodent, Rio de Janeiro, RJ, Brazil) and Vitro Fill (DFL, Rio de
Aurilene S Cardoso   +5 more
doaj   +1 more source

Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates

open access: yesNature Communications, 2020
Antibody-drug conjugates targeting high expression receptors can suffer from poor tumour penetration. Here, the authors use unconjugated antibody to improve the penetration of an antibody-dye conjugate in a clinical study, supporting further clinical ...
Guolan Lu   +8 more
doaj   +1 more source

Effect of Calendering and Surface Treatment on the Thermochromic Response of Cholesteric Liquid Crystals on PET Nonwovens

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the influences of calendering and surface treatment during direct ink writing (DIW) of thermochromic cholesteric liquid crystal (CLC) on PET nonwovens. For the PVA‐coated nonwovens, calendering reduces pore size leading to reduced ink absorption and enhanced spreading. The NeverWet‐coated nonwovens improve thermochromic responses by
Sreenivasan Sreenivasan Narayanan   +3 more
wiley   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

open access: yesAdvanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein   +4 more
wiley   +1 more source

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