Results 61 to 70 of about 314,977 (308)

A Proposal to Restructure Hospital Care for Dying Patients

, 1996
Data from the recent Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments (SUPPORT) indicate that the care of hospitalized dying patients continues to be inadequate.
Fins, Joseph J., Miller, Franklin G.
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Using Palliative Care Needs Rounds in the UK for care home staff and residents: an implementation science study

Health and Social Care Delivery Research
Background Care home residents often lack access to end-of-life care from specialist palliative care providers. Palliative Care Needs Rounds, developed and tested in Australia, is a novel approach to addressing this.
Liz Forbat, Aisha Macgregor, Karen Spilsbury, Brendan McCormack, Alasdair Rutherford, Barbara Hanratty, Jo Hockley, Lisa Davison, Margaret Ogden, Irene Soulsby, Maisie McKenzie   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Life and death in English nursing homes : sequestration or transition? [PDF]

, 2001
Nursing homes as care institutions seek to offer a home where people can live until their death. A potential conflict, therefore, exists as nursing homes are both a place where life is lived and where death is regularly encountered.
Froggatt, Katherine A.
core  

Attitudes of Iranian nurses toward caring for dying patients

, 2008
Objective: To examine the attitudes of Iranian nurses toward caring for dying patients.Methods: Nurses' attitudes toward death and caring for dying patients were examined by using two types of questionnaires: the Death Attitude Profile-Revised (DAP-R ...
Abbaszadeh, Abbas, Dargahi, Helen,, Iranmanesh, Sedigheh,, Iranmanesh, Sedigheh, Abbaszadeh, Abbas,, Dargahi, Helen   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Approaching the end of life and dying with dementia in care homes : the accounts of family carers. [PDF]

, 2010
Research into end of life and dying with dementia in care homes from the family carer's perspective is limited. From the available evidence, it appears that family carers find themselves in an unfamiliar situation about which they lack knowledge and ...
Keady, J., Froggatt, Katherine, Hennings, J., Keady, J.; id_orcid, Froggatt, K.   +4 more
core   +1 more source