Results 101 to 110 of about 24,196,663 (244)

Folder 6: Model engine data sheets and operating instructions, J - N, ca. 1960, 1972, 1988

open access: yes, 1960
Instructions, illustrations, and parts price list for a Dynamic Models, INC. Johnson Engines.
Dynamic Models, Inc.
core  

Comparison of Dynamic Data Analysis Methods for Thermal Property Measurement of a Building Wall [PDF]

open access: yes, 2006
Energy usage in heating and air-conditioning a building is influenced by several factors. Among them is the building wall, whose production is affected by the planning, design and construction process.
Gong, Y., Huang, K.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Advances in capillary electrophoresis: In-line preconcentration for biomedical analysis. Impurity profiling of heparin [PDF]

open access: yes, 2015
Capillary electrophoresis (CE) has shown to be highly suitable for the analysis of polar and ionogenic compounds in biomedical and pharmaceutical samples. Separation with CE is based on the charge-to-size ratio of analytes.
van der Hoorn, Y.H.   +2 more
core  

On the Generalized Hilfer Fractional Coupled Integro-Differential Systems with Multi-Point Ordinary and Fractional Integral Boundary Conditions

open access: yesAxioms
In this paper, we investigate a nonlinear coupled integro-differential system involving generalized Hilfer fractional derivative operators ((k,ψ)-Hilfer type) of different orders and equipped with non-local multi-point ordinary and fractional integral ...
Chayapat Sudprasert   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

MonoBot: A Single-Actuator Walking Robot

open access: yesIEEE Access
This paper introduces the design and analysis of novel planar mobile robot operated by a single actuator. Distinct from conventional multi-actuator designs, this robot achieves both walking and turning motions through a single actuator mechanism, thereby
Uriya Lax, Oded Medina, Nir Shvalb
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Home - About - Disclaimer - Privacy