Results 121 to 130 of about 24,196,663 (244)

Evaluation of Seismic Response of the Cross-Laminated Timber (CLT) Multi-Storey Residential Building Under the February 6, 2023, Kahramanmaraş Earthquakes

open access: yesJournal of Architectural Sciences and Applications
The February 6, 2023 Kahramanmaraş earthquakes exposed the vulnerabilities of existing RC structures, causing thousands of buildings to collapse or sustain severe damage, especially in the hardest-hit provinces.
Gülten Tandoğan Kibar   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Multiple positive solutions for dynamic m-point boundary value problems

open access: yes, 2008
In this paper, we consider a second order m-point boundary value problem for dynamic equations on time scales. First, we establish criteria for the existence of one or more than one positive solution of a non-eigenvalue problem.
Karaca, Ilkay Yaslan
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A simple dynamic analysis

open access: yes, 1998
Centro de Informacion y Documentacion Cientifica (CINDOC). C/Joaquin Costa, 22. 28002 Madrid.
Barcelona Univ. Autonoma, Bellaterra (Spain). Dept. de Economia y de Historia Economica   +2 more
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Analysis of Design Process Dynamics.

open access: yes, 2004
To enable the development of automated support for design, a challenge is to model and analyse dynamics of design processes in a formal manner. This paper contributes a declarative, logical approach for specification of dynamic properties of design processes, supported by a formal temporal language.
Bosse, T., Jonker, C.M., Treur, J.
openaire   +4 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Computational Method for Dynamic Analysis of Multibody Systems with Deformable Elements

open access: yesMathematics
The dynamics of mechanical systems with fast motions and dynamic loads are strongly influenced by the deformability of kinematic elements. The finite element method and the superposition of rigid body motion with deformable body motion allow us to ...
Sorin Dumitru   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Home - About - Disclaimer - Privacy