Results 111 to 120 of about 32,127,622 (336)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Effects of twin-boundary precipitates on twin stability and yield strength of a Mg-Nd-Ag-Zr alloy

open access: yesJournal of Materials Research and Technology
The effects of precipitates at {10 1‾ 2} twin boundaries on twin stability and yield strength of a Mg-Nd-Ag-Zr alloy are investigated by transmission electron microscopy and electron back-scattered diffraction.
X.J. Zhao   +6 more
doaj   +1 more source

High-impact dynamic-response analysis of nonlinear structures [PDF]

open access: yes, 1971
Program predicts expected deformations and stresses in nonlinear simple geometric structures subjected to high-impact loading. Technique is based on node-wise predictor-corrector approach and requires moderate computer storage and run time for most ...
Gupta, K. K.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Integration and marginalization in second-generation immigrants in Palermo: an empirical research

open access: yesInternational Journal of Psychoanalysis and Education, 2019
In recent decades, Italy has been affected by constant migratory flows of people, which have brought substantial changes to the social, cultural and economic structure of the country.There are, in fact, many second-generation immigrants on the national ...
Serena Giunta   +2 more
doaj  

Dynamic Malware Analysis in the Modern Era—A State of the Art Survey

open access: yesACM Computing Surveys, 2019
Although malicious software (malware) has been around since the early days of computers, the sophistication and innovation of malware has increased over the years.
Ori Or-Meir   +3 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A family of droids -- Android malware detection via behavioral modeling: static vs dynamic analysis [PDF]

open access: yes, 2019
Following the increasing popularity of mobile ecosystems, cybercriminals have increasingly targeted them, designing and distributing malicious apps that steal information or cause harm to the device's owner.
Almeida, Mario   +5 more
core  

Dynamic Analysis of Executables to Detect and Characterize Malware

open access: yes, 2018
It is needed to ensure the integrity of systems that process sensitive information and control many aspects of everyday life. We examine the use of machine learning algorithms to detect malware using the system calls generated by executables-alleviating ...
Aimone, James B.   +6 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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