Results 161 to 170 of about 31,271,570 (411)
QUEUEING ANALYSIS FOR TRAFFIC CONTROL WITH COMBINED CONTROL OF DYNAMIC MMPP ARRIVALS AND TOKEN RATES [PDF]
, 2013 Doo Il Choi
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Computational Method for Dynamic Analysis of Multibody Systems with Deformable Elements
MathematicsThe dynamics of mechanical systems with fast motions and dynamic loads are strongly influenced by the deformability of kinematic elements. The finite element method and the superposition of rigid body motion with deformable body motion allow us to ...
Sorin Dumitru +3 more
doaj +1 more source
Vehicle-bridge dynamic interaction using finite element modelling
, 2010 First investigations on the dynamic response of bridges due to moving loads were motivated by the collapse of the Chester railway bridge in the UK in the middle of the 19th century.
Arturo Gonzalez, González, Arturo
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Magazine of Civil EngineeringThe article presents the results of the research of the emergency loads effect on reinforced concrete turbine foundations of different types. Computational experiments were performed in a specialized finite element analysis program NX/NASTRAN ...
Abu-Khasan Mahmud +4 more
doaj +1 more source
Dynamic Factor Analysis with ARMA Factors [PDF]
In this paper we present a new approach to the specification of dynamic factor models. Our model has three advantages over existing work. Firstly, it is based on a minimal-dimension state-space representation giving some gain in computational efficiency ...
Victor Solo, Chris Heaton
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source