Results 61 to 70 of about 734,048 (269)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Refined Seismic Design Method for RC Frame Structures to Increase the Collapse Resistant Capacity
Applied Sciences, 2020 In current structural design codes, elastic vibration modes are used for seismic design. However, when a structure is subjected to strong earthquakes and inelastic response or even when collapse damage is observed, the damage state is always unevenly ...
Mengmeng Gao, Shuang Li
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Blast Performance of Multi-Layer Composite Door Panel with Energy Absorption Connectors
BuildingsDoors are considered vulnerable to failure in structures when subjected to extreme loads, such as blasts. Consequently, blast-resistant doors are designed to withstand blast pressure in important structures.
Shahab Ahmad +3 more
doaj +1 more source
Advances in Civil Engineering, 2020 This paper presents the results of an experimental research designed to investigate the combined effects of corrosion rate, concrete cover thickness, and stirrup spacing on the bond performance between reinforcement and concrete of reinforced concrete ...
Yubin Tian +6 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Constant Ductility Site-Specific Yield Point Spectra for Seismic Design
Advances in Civil Engineering, 2019 Displacement-based seismic design (DBSD) is an iterative process because the strength and stiffness of a structure are needed to be adjusted in order to achieve a specific performance level, which is extremely inconvenient for designers in practice ...
Duofa Ji, Weiping Wen, Changhai Zhai
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Response of RPC-Filled Circular Steel Tube Columns under Monotonic and Cyclic Axial Loading
Shock and Vibration, 2019 Results from mechanical tests on thirteen reactive powder concrete- (RPC-) filled circular steel tube (RFCT) columns under monotonic and cyclic axial loading are presented in this paper.
Qin Rong +4 more
doaj +1 more source