Results 51 to 60 of about 28,075 (149)

Blast Performance of Multi-Layer Composite Door Panel with Energy Absorption Connectors

open access: yesBuildings
Doors are considered vulnerable to failure in structures when subjected to extreme loads, such as blasts. Consequently, blast-resistant doors are designed to withstand blast pressure in important structures.
Shahab Ahmad   +3 more
doaj   +1 more source

Experimental Study on Bond Performance and Damage Detection of Corroded Reinforced Concrete Specimens

open access: yesAdvances in Civil Engineering, 2020
This paper presents the results of an experimental research designed to investigate the combined effects of corrosion rate, concrete cover thickness, and stirrup spacing on the bond performance between reinforcement and concrete of reinforced concrete ...
Yubin Tian   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Constant Ductility Site-Specific Yield Point Spectra for Seismic Design

open access: yesAdvances in Civil Engineering, 2019
Displacement-based seismic design (DBSD) is an iterative process because the strength and stiffness of a structure are needed to be adjusted in order to achieve a specific performance level, which is extremely inconvenient for designers in practice ...
Duofa Ji, Weiping Wen, Changhai Zhai
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Response of RPC-Filled Circular Steel Tube Columns under Monotonic and Cyclic Axial Loading

open access: yesShock and Vibration, 2019
Results from mechanical tests on thirteen reactive powder concrete- (RPC-) filled circular steel tube (RFCT) columns under monotonic and cyclic axial loading are presented in this paper.
Qin Rong   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Experimental and Numerical Study on Plastic Behavior of Expansion Tubes Subjected to Impact

open access: yesApplied Sciences
Aiming to study the plastic behavior of expansion tubes, this paper presents experimental studies on Q420 and S2205 steel tubes and investigates the influence of key parameters on the responses of the expansion tube. A finite element model is established
Di Jiang   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy