Results 71 to 80 of about 249,357 (259)

Narcissistic CEOs, dynamic capability, and green innovation. [PDF]

Heliyon, 2023
Chang L, Liang R, Zhang J, Yan X, Tao H, Zhu T.   +5 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

How Dynamic Capabilities and Ambidextrous Learning Shape SME Innovation Performance: The Moderating Role of Exploratory and Exploitative Learning

Systems
This study examines the differential effects of three dimensions of dynamic capabilities on innovation performance and investigates how ambidextrous learning (exploratory and exploitative learning) moderates these relationships.
Yonghong Ma, Zihui Wei
doaj   +1 more source

Modeling the significance of dynamic capability on the performance of microfinance institutions. [PDF]

PLoS One, 2023
The HV, Yang M, Fazal SA, Maran, Gao J, Yang Q, Al Mamun A.   +6 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Linking Frontline Employee Self-Efficacy to Customers Service Performance in Healthcare Industry: A Dynamic Capability Perspective. [PDF]

Risk Manag Healthc Policy, 2023
Li R, Liu J, Xia W, Ma J.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Role of Strategic Orientations in the Relationship Between Adaptive Marketing Capabilities and Ambidexterity in Digital Services Firms: The Case of a Highly Competitive Digital Economy

Systems
As the digital economy progresses aggressively in the UAE, the ways in which different players in the economy interact with each other are changing. Therefore, strategic orientations that enable successful interactions have become a necessity. This study
Madhad Ali Said Al Jabri, Abdelmounaim Lahrech   +1 more
doaj   +1 more source

Competitive positioning and market share of selected insurance companies: case of Nigeria [PDF]

Insurance Markets and Companies
The insurance industry contributes to the smooth running of the economy. Unfortunately, not every country develops insurance at a high level; that is, the level of insurance penetration is low. This is happening in Nigeria.
Ajetunmobi Ololade A., Adesoga Adefulu, Makinde Grace Olubisi, Nwankwere Idowu   +3 more
doaj   +1 more source