Results 131 to 140 of about 5,911,579 (291)

Large-scale neural models and dynamic causal modelling

open access: yesNeuroImage, 2006
Dynamic causal modelling (DCM) is a method for estimating and making inferences about the coupling among small numbers of brain areas, and the influence of experimental manipulations on that coupling [Friston, K.J., Harrison, L., Penny, W., 2003 Dynamic causal modelling. Neuroimage 19, 1273-1302].
Lucy Lee, Karl J. Friston, Barry Horwitz
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Traffic Flow Prediction in Complex Transportation Networks via a Spatiotemporal Causal–Trend Network

open access: yesMathematics
Traffic systems are quintessential complex systems, characterized by nonlinear interactions, multiscale dynamics, and emergent spatiotemporal patterns over complex networks.
Xingyu Feng   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Dynamic Business Modeling for Sustainability

open access: yes, 2022
In the last decade, both sustainability (Green & Blue Economies) and business models for sustainability (BMfS) have increased in importance. Social life cycle sustainability assessment has not fully achieved goal, mainly because sustainability ...
Lin, Jing   +3 more
core   +1 more source

Causal Geometry and Irreversibility in Human Cognition and AI Alignment

open access: yes
This project presents an initial conceptual framework that applies causal and geometric structures inspired by relativity theory to human cognition and AI alignment.
Causal Geometry Research
core   +1 more source

Causal Modeling of Dynamical Systems

open access: yes, 2018
54 ...
Bongers, Stephan   +2 more
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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