Results 61 to 70 of about 5,911,579 (291)

Taking Causal Modeling to a Next Level:Self-Modeling Networks Adding Adaptivity to Causality [PDF]

open access: yes, 2020
This paper covers the contents of a Keynote Speech with the same title. Causal modeling is an intuitive, declarative way of modeling that due to the universal character of causality in principle applies to practically all disciplines.
Treur, Jan; id_orcid
core   +1 more source

A fast dynamic causal modeling regression method for fMRI

open access: yesNeuroImage
Dynamic Causal Modeling (DCM) is a crucial tool for studying brain effective connectivity, offering valuable insights into brain network dynamics through functional magnetic resonance imaging (fMRI) and electrophysiology (EEG and MEG).
Haifeng Wu, Xinhang Hu, Yu Zeng
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

Attentional Enhancement of Auditory Mismatch Responses: a DCM/MEG Study. [PDF]

open access: yes, 2015
Despite similar behavioral effects, attention and expectation influence evoked responses differently: Attention typically enhances event-related responses, whereas expectation reduces them.
Auksztulewicz, R, Friston, K
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

From prediction to intervention: causal digital twins for personalized clinical decision support

open access: yesJournal of Translational Medicine
Objective This work proposes a unified framework for causal digital twins, integrating Structural Causal Models (SCMs), the Potential Outcomes Framework, and reinforcement learning.
Alexandre Vallée
doaj   +1 more source

Dysconnectivity in the frontoparietal attention network in schizophrenia

open access: yesFrontiers in Psychiatry, 2013
Cognitive impairment is common in patients with schizophrenia (SZs), and even those with relatively preserved function perform worse than healthy volunteers (HVs) on attentional tasks.
Jonathan P Roiser   +7 more
doaj   +1 more source

Causal Discovery of Stochastic Dynamical Systems: A Markov Chain Approach

open access: yesMathematics, 2023
Our proposed method for exploring the causal discovery of stochastic dynamic systems is designed to overcome the limitations of existing methods in detecting hidden and common drivers.
Marcell Stippinger   +4 more
doaj   +1 more source

Discovering Brain Mechanisms Using Network Analysis and Causal Modeling [PDF]

open access: yes, 2017
Mechanist philosophers have examined several strategies scientists use for discovering causal mechanisms in neuroscience. Findings about the anatomical organization of the brain play a central role in several such strategies.
Naftali Weinberger   +3 more
core   +1 more source

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