Results 21 to 30 of about 21,276,656 (224)

A study on development of a work instruction system for assembly cells based on analysis of learning processes

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
A cellular manufacturing system is a kind of lean and flexible manufacturing systems in which a worker or a group of workers carry out all assembly processes of a product.
Yoshitaka TANIMIZU   +2 more
doaj   +1 more source

Designing a Dynamic and Sustainable Cellular Manufacturing System by Considering the Amount of Energy Consumption and Manpower in Production Planning [PDF]

open access: yesمجله مدل سازی در مهندسی
The design and planning of cellular Manufacturing systems in most classical models is based on minimizing production costs or increasing producers' profits.
Nader Ghanei   +2 more
doaj   +1 more source

A framework for manufacturing system reconfiguration and optimisation utilising digital twins and modular artificial intelligence [PDF]

open access: yes, 2023
Digital twins and artificial intelligence have shown promise for improving the robustness, responsiveness, and productivity of industrial systems. However, traditional digital twin approaches are often only employed to augment single, static systems to ...
Chaplin, Jack C.   +15 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A Benders� Decomposition Approach for Dynamic Cellular Manufacturing System in the Presence of Unreliable Machines [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2015
In order to implement the cellular manufacturing system in practice, some essential factors should be taken into account. In this paper, a new mathematical model for cellular manufacturing system considering different production factors including ...
Masoud Bagheri   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Designing a manufacturing cell system by assigning workforce

open access: yesJournal of Industrial Engineering and Management, 2019
Purpose: In this paper, we have proposed a new model for designing a Cellular Manufacturing System (CMS) for minimizing the costs regarding a limited number of cells to be formed by assigning workforce. Design/methodology/approach: Pursuing mathematical
Ashkan Ayough, Behrouz Khorshidvand
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Optimisation of transmission bandwidth for indoor cellular OWC system using a dynamic handover decision-making algorithm [PDF]

open access: yes, 2012
In this paper, we propose a novel cellular optical wireless communications (COWC) system with four diffused cells. A dynamic handover scheme is proposed to make the link more flexible by the way of adaptive channel allocation in different environments ...
Rajbhandari, S   +14 more
core   +1 more source

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