Cellular manufacturing system evolution from group technology to a reconfigurable manufacturing system: A case study of a dynamic cellular manufacturing system (DCMS) in an electromechanical assembly industry [PDF]
, 2017 This chapter defines some characteristics of the Cellular Manufacturing System (CMS), and explores the most important features from the literature and the practices that can be used to develop a Dynamic Cellular Manufacturing System (DCMS).
Gamache, S., Abdul-Nour, G., Nouri, K.
core +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Reconfigurable manufacturing system design: The case of mobile manufacturing system [PDF]
, 2014 Mobile manufacturing is an enabler to increase the possibility to change and to adapt to altering needs, where the geographical position is not fixed.
BENAMA, Youssef +5 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Evaluation of cellular manufacturing configurations in dynamic conditions using simulation
, 2011 This paper investigates the performance of classical cellular manufacturing systems compared to other two systems proposed in literature: fractal cells and remainder cells.
Paolo Renna +3 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Toward functionally graded cellular microstructures [PDF]
, 2009 The design of multifunctional materials offers great potential for numerous applications in areas ranging from biomaterial science to structural engineering.
Corney, J.R., Torres-Sanchez, C.
core +4 more sources
A simulated annealing algorithm to determine a group layout and production plan in a dynamic cellular manufacturing system [PDF]
Journal of Optimization in Industrial Engineering, 2014 In this paper, a mixed-integer linearized programming (MINLP) model is presented to design a group layout (GL) of a cellular manufacturing system (CMS) in a dynamic environment with considering production planning (PP) decisions.
Reza KiA +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source