Results 61 to 70 of about 527,575 (266)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Large-scale dynamic triaxial tests on saturated gravel soil in Nanning metro area
Yantu gongcheng xuebao, 2019 The gravel soil in Nanning metro area is taken as the research object, and a series of large-scale drained dynamic triaxial tests are conducted on saturated gravel.
MA Shao-kun 1,2, WANG Bo 1, LIU Yin 1,2, SHAO Yu 1,3,5, WANG Hong-gang 1, WANG Yan-li 4
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
SystemsProduct development is a complex process involving intricate components, dynamics and constantly evolving internal and external environments, as well as numerous influencing factors.
Fupeng Yin, Qi Gao, Jiakun Sun
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
LubricantsThe gear transmission system occupies a core position in mechanical equipment due to its numerous advantages such as high efficiency, high reliability, and long durability, making it an indispensable key component.
Yihong Gu, Lin Li, Gaoan Zheng
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Characteristics of wideband dipole phased array of L-band
Известия высших учебных заведений России: Радиоэлектроника, 2015 Results of designing of broadband equidistant phased antenna array (PAA) of UHF range, built on the basis of dipole emitters are shown. Frequency dependences of the reflection coefficients in the path of the power elements in the infinite PAA, as well as
S. V. Ballandovich +4 more
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