Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Charge-on-the-move solutions for future mobility: A review of current and future prospects
The electrification of transportation has emerged as a key focus area over the past decade, driven by the rise of electric vehicles (EVs) and supportive governmental policies.
Mohd Aiman Khan +4 more
doaj +1 more source
Analysis and Case Study of National Economic Evaluation of Expressway Dynamic Wireless Charging
As the transportation industry develops new forms of energy and electrification, expressway dynamic wireless charging has become an attractive technology that has the potential to completely solve a range of anxieties associated with electric vehicles ...
Siqi Li +3 more
doaj +1 more source
Dynamics of charges and solitons
We first show that trajectories traced by charges moving in rotational magnetic fields are are, basically, the non-parallel geodesics of surfaces of revolution with coincident axis. Thus, people living in a surface of revolution are not able to sense the magnetic Hall e↵ect induced by the surrounding magnetic field and perceive charges as influenced ...
Barros, Manuel +2 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Materials Characterization at Utah State University: Facilities and Knowledgebase of Electronic Properties of Materials Applicable to Spacecraft Charging [PDF]
In an effort to improve the reliability and versatility of spacecraft charging models designed to assist spacecraft designers in accommodating and mitigating the harmful effects of charging on spacecraft, the NASA Space Environments and Effects (SEE ...
Corbridge, Jodie +4 more
core +1 more source
Implementation of Dynamic Charging and V2G using Chademo and CCS/Combo DC charging standard
Dynamic charging of electric vehicles (EV) refers to charging the EV using variable charging power. This is important for applications where the EV is charged from intermittent renewable energy sources like wind or solar.
Pavol Bauer +7 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Segmental Track Analysis in Dynamic Wireless Power Transfer
Electric vehicles have gained more and more attention because of the serious oil crisis and environmental problems. However, the disadvantages of the electric vehicle, such as short driving range, high battery cost, and inconvenient charging, are ...
Shi-Chun Yang +8 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

