Results 71 to 80 of about 3,060,651 (293)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Hybrid energy storage system for fast and efficient electric vehicle charging [PDF]

The rapid adoption of electric vehicles (EVs) necessitates efficient and fast charging solutions to meet growing energy demands. This study introduces a hybrid energy storage system (HESS) designed to enhance EV charging performance.
Abd Rahim, Rosemizi bin, Fahmi Romli, Muhammad Izuan, Fang, Liew Hui   +2 more
core   +1 more source

Synergy effects of dynamic and stationary charging systems along motorways

European Transport Studies
Electric vehicles have the potential to positively impact traffic-related CO2-emissions in the transport sector, thereby promoting the transition towards a more sustainable road transport system.
Christian Roland Hein, M.Sc., Danny Wauri, Alexander Hepp, David Petermann, Sahil Khan, Ömer Turgut, Barbara Först   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Segmental Track Analysis in Dynamic Wireless Power Transfer

Energies, 2019
Electric vehicles have gained more and more attention because of the serious oil crisis and environmental problems. However, the disadvantages of the electric vehicle, such as short driving range, high battery cost, and inconvenient charging, are ...
Shi-Chun Yang, Hong He, Xiao-Yu Yan, Yu-Hang Chen, Yang Hua, Yao-Guang Cao, Jun Li, Hong-Hai Li, Sheng Yin   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Older People’s Attitudes to Road Charging: Are They Distinctive and What are the Implications for Policy? [PDF]

, 2011
In an ageing society older people have a growing influence on politics in general, and potentially on the acceptability of road charging in particular. They face specific types of risk of transport-related social exclusion which may influence their views
Nikitas, Alexandros, Parkhurst, Graham, Erel Avineri, Graham Parkhurst, Avineri, Erel, Alexandros Nikitas   +5 more
core   +1 more source

Static and dynamic correlations in a charged membrane [PDF]

Physical Review E, 2006
We study static and dynamic correlations of two fluctuations, the charge density fluctuation and height fluctuation (undulation), on a fluid membrane with a finite excess charge in a viscous fluid. For a planar and symmetrical membrane, we consider a model Hamiltonian inclusive of the fluctuations at the Gaussian level, and construct their equations of
Sung, WK, Choi, EJ, Kim, YW Kim, Yong Woon   +2 more
openaire   +3 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source