Results 41 to 50 of about 3,107,467 (149)

C-clamp and pelvic packing for control of hemorrhage in patients with pelvic ring disruption [PDF]

, 2011
BACKGROUND: Exsanguinating hemorrhage is the major cause of death in patients with pelvic ring disruption. AIMS: The aim of this study was to document outcomes after the stabilization of pelvic ring injuries by a C-clamp and control of hemorrhage ...
Meier, C, Lustenberger, T, Benninger, Emanuel, Lenzlinger, Philipp M, Keel, M J B, Benninger, E, Keel, Marius Johann Baptist, Lustenberger, Thomas, Lenzlinger, Philipp M., Meier, Christoph, Keel, Marius J B, Lenzlinger, P M, Keel, Marius   +12 more
core   +1 more source

A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time

Frontiers in Physiology, 2018
An important aspect of the Comprehensive In Vitro Proarrhythmia Assay (CiPA) proposal is the use of human stem cell-derived cardiomyocytes and the confirmation of their predictive power in drug safety assays.
Birgit Goversen, Nadine Becker, Sonja Stoelzle-Feix, Alison Obergrussberger, Marc A. Vos, Toon A. B. van Veen, Niels Fertig, Teun P. de Boer   +7 more
doaj   +1 more source

Patch-clamp and multi-electrode array electrophysiological analysis in acute mouse brain slices

STAR Protocols, 2021
Summary: Patch-clamp and multi-electrode array electrophysiology techniques are used to measure dynamic functional properties of neurons. Whole-cell and cell-attached patch-clamp recordings in brain slices can be performed in voltage-clamp and current ...
Kevin M. Manz, Justin K. Siemann, Douglas G. McMahon, Brad A. Grueter   +3 more
doaj   +1 more source

The dendritic location of the L-type current and its deactivation by the somatic AHP current both contribute to firing bistability in motoneurons

Frontiers in Computational Neuroscience, 2014
Spinal motoneurons may display a variety of firing patterns including bistability between repetitive firing and quiescence and, more rarely, bistability between two firing states of different frequencies.
Marin eManuel, Daniel eZytnicki, Claude eMeunier   +2 more
doaj   +1 more source

A Reconfigurable Visual-Programming Library for Real-time Closed-loop Cellular Electrophysiology

Frontiers in Neuroinformatics, 2015
Most of the software platforms for cellular electrophysiology are limited in terms of flexibility, hardware support, ease of use, or re-configuration and adaptation for non-expert users.
István eBiró, Michele eGiugliano, Michele eGiugliano, Michele eGiugliano   +3 more
doaj   +1 more source

Design strategy of IGCT clamp circuit parameters based on bi-objective nonlinear optimization

Energy Reports, 2022
The integrated gate commutated thyristor (IGCT) is a high-power semiconductor device with excellent performance, whose operating characteristics are governed by the clamp circuit.
Tao Jiang, Xiaotao Han, Shaozhe Zhang
doaj   +1 more source

Functional correlates of clinical phenotype and severity in recurrent SCN2A variants

Communications Biology, 2022
A comprehensive biophysical analysis of disease-associated mutations in the voltage-gated sodium channel gene, SCN2A, suggests that dynamic action potential clamp may be a better predictor than voltage clamp of how these mutations alter neuronal ...
Géza Berecki, Katherine B. Howell, Jacqueline Heighway, Nelson Olivier, Jill Rodda, Isabella Overmars, Danique R. M. Vlaskamp, Tyson L. Ware, Simone Ardern-Holmes, Gaetan Lesca, Michael Alber, Pierangelo Veggiotti, Ingrid E. Scheffer, Samuel F. Berkovic, Markus Wolff, Steven Petrou   +15 more
doaj   +1 more source

The human dynamic clamp as a paradigm for social interaction [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance The human dynamic clamp (HDC) is proposed as a general paradigm for studies of elementary forms of social behavior in complex biological systems. HDC enables parametric control of real-time bidirectional interaction between humans and empirically grounded theoretical models of coordination dynamics.
Guillaume, Dumas, Gonzalo C, de Guzman, Emmanuelle, Tognoli, J A Scott, Kelso   +3 more
openaire   +2 more sources

Statistics of neuronal identification with open and closed loop measures of intrinsic excitability

Frontiers in Neural Circuits, 2012
In complex nervous systems patterns of neuronal activity and measures of intrinsic neuronal excitability are often used as criteria for identifying and/or classifying neurons.
Ted eBrookings, Rachel eGrashow, Eve eMarder   +2 more
doaj   +1 more source

Classical and numerical approaches to determining V-section band clamp axial stiffness [PDF]

, 2014
V-band clamp joints are used in a wide range of applications to connect circular flanges, for ducts, pipes and the turbocharger housing. Previous studies and research on V-bands are either purely empirical or analytical with limited applicability on the ...
Khodabakhshi, Goodarz, Barrans, Simon, Muller, Matthias, Khodabakhshi Goodarz, Barrans, Simon M., Muller Matthias, Barrans Simon M.   +6 more
core   +1 more source