Results 21 to 30 of about 477 (209)
Cell Reports, 2022 Summary: Protein machines undergo conformational motions to interact with and manipulate polymeric substrates. The Sec translocase promiscuously recognizes, becomes activated, and secretes >500 non-folded preprotein clients across bacterial cytoplasmic ...
Srinath Krishnamurthy +10 more
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The Phylogenetics of Dynamics in DNA Clamp Proteins [PDF]
Structure, 2014 Using HXMS to measure protein dynamics, Fang and colleagues (in this issue of Structure) probe the dynamics of processivity clamp proteins from all kingdoms of life. The proteins have similar structures but divergent sequences. Their results show conserved dynamics correlating with primary functions and divergent dynamics for divergent functions.
Balasubramaniam, Deepa +1 more
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Causes of Transient Instabilities in the Dynamic Clamp [PDF]
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2009 The dynamic clamp is a widely used method for integrating mathematical models with electrophysiological experiments. This method involves measuring the membrane voltage of a cell, using it to solve computational models of ion channel dynamics in real-time, and injecting the calculated current(s) back into the cell. Limitations of this technique include
Amanda J, Preyer, Robert J, Butera
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Synchronisation through nonreciprocal connections in a hybrid hippocampus microcircuit
Frontiers in Neural Circuits, 2013 Synchronisation among neurons is thought to arise from the interplay between excitation and inhibition; however, the connectivity rules that contribute to synchronisation are still unknown.
Markus M Hilscher +2 more
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Frontiers in Cell and Developmental Biology, 2020 Atrial fibrillation (AF) is the most common cardiac arrhythmia. About 5–15% of AF patients have a mutation in a cardiac gene, including mutations in KCNA5, encoding the Kv1.5 α-subunit of the ion channel carrying the atrial-specific ultrarapid delayed ...
Sarah Hilderink +5 more
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Patch-clamp and multi-electrode array electrophysiological analysis in acute mouse brain slices
STAR Protocols, 2021 Summary: Patch-clamp and multi-electrode array electrophysiology techniques are used to measure dynamic functional properties of neurons. Whole-cell and cell-attached patch-clamp recordings in brain slices can be performed in voltage-clamp and current ...
Kevin M. Manz +3 more
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Dynamics of a clamped–clamped microbeam resonator considering fabrication imperfections [PDF]
Microsystem Technologies, 2014 We present an investigation into the static and dynamic behavior of an electrostatically actuated clamped---clamped polysilicon microbeam resonator accounting for its fabrication imperfections, which are commonly encountered in similar microstructures.
Bataineh, Ahmad M., Younis, Mohammad I.
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Frontiers in Computational Neuroscience, 2014 Spinal motoneurons may display a variety of firing patterns including bistability between repetitive firing and quiescence and, more rarely, bistability between two firing states of different frequencies.
Marin eManuel +2 more
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A Reconfigurable Visual-Programming Library for Real-time Closed-loop Cellular Electrophysiology
Frontiers in Neuroinformatics, 2015 Most of the software platforms for cellular electrophysiology are limited in terms of flexibility, hardware support, ease of use, or re-configuration and adaptation for non-expert users.
István eBiró +3 more
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Design strategy of IGCT clamp circuit parameters based on bi-objective nonlinear optimization
Energy Reports, 2022 The integrated gate commutated thyristor (IGCT) is a high-power semiconductor device with excellent performance, whose operating characteristics are governed by the clamp circuit.
Tao Jiang, Xiaotao Han, Shaozhe Zhang
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