Results 121 to 130 of about 64,005 (305)

Development of a front end ASIC for Dark Matter directional detection with MIMAC

, 2010
A front end ASIC (BiCMOS-SiGe 0.35 \mum) has been developed within the framework of the MIMAC detector project, which aims at directional detection of non-baryonic Dark Matter.
Ahlen, Allaoua, Boni, C. Grignon, D. Santos, Dzahini, F. Mayet, G. Bosson, Giomataris, Giomataris, Green, Grignon, J.P. Richer, Linan-Cembrano, Mayet, O. Bourrion, O. Guillaudin, Santos, Spergel   +18 more
core   +3 more sources

Short‐Term Scheduling Optimization of a Single‐Pipeline Refining System With High Melting Point Crude Oil

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao, Xianxin Liu, Zhen Pan, Chengming Hao, Xiangwei Xu, Wei Jia   +5 more
wiley   +1 more source

Tranexamic Acid Use in Hip Arthroscopy Reduces Bleeding Without Increased Risk of Major Complications: A Systematic Review

Arthroscopy, EarlyView.
Purpose To critically evaluate the impact of tranexamic acid (TXA) on hip arthroscopy outcomes, including its effects on bleeding, functional recovery, postoperative pain, complications, intraoperative visualization, and surgical efficiency. Methods A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic ...
Paul B. Walker, Mathangi Sridharan, Adrian Lin, Atousa Nourmahnad, Alexander Fish, Sharon L. Hame, Kristofer J. Jones   +6 more
wiley   +1 more source

The impact of a preprescribing formative assessment on learning in final‐year medical students using hospital inpatient electronic prescribing systems

British Journal of Clinical Pharmacology, EarlyView.
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles, Lorna Pairman, Emily Moon, Daniel Wong, John Quayle, Tim J. Wilkinson, Matthew Doogue, Paul Chin   +7 more
wiley   +1 more source

Simple first order data compression processor concept [PDF]

, 1967
Data-compression processing systems based on an analog-to-digital converter /ADC/, includes a qualitative comparator for comparison of the ADC output with a ramp generator, which is connected as a bidirectional binary counter with selective inputs.
Anderson, T. O.
core   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

A 10‐bit 13.3 µW single‐slope analog‐to‐digital converter with auto‐zero power‐down technique

Electronics Letters
This letter presents a low‐power single‐slope analog‐to‐digital converter (ADC) for column‐parallel architectures. A simple and effective design technique is proposed to solve the input‐dependent power consumption problem of the conventional single‐slope
Youngwoo Lee, Suhwan Kim, Jaehoon Jun
doaj   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source