Effectiveness and Safety of RHA3 vs a Comparator Product for Lip Augmentation: A Randomized, Controlled, Prospective, Multicenter Clinical Study. [PDF]
Weinkle S +8 more
europepmc +1 more source
Abstract Objective To determine whether computational protein‐stability predictions discriminate pathogenic from benign SCN1A missense variants, and to characterize the structural distribution of predicted destabilization among pathogenic variants. Methods On an AlphaFold3‐predicted Nav1.1 structure, FoldX, and Rosetta Cartesian ΔΔG were computed for a
Youngkyu Shim +3 more
wiley +1 more source
The Implementation of a Business Process Model and Notation for Modeling Patient Health Care Trajectories: Systematic Review. [PDF]
Gartner JB +7 more
europepmc +1 more source
ABSTRACT Gender incongruence in trans and nonbinary (“trans”) populations is often associated with psychological distress and increased demand for mental healthcare. Gender‐affirming hormone therapy (GAHT) is a key component of care for many trans people, yet long‐term evidence around its cost implications remains limited despite increasing uptake and ...
Karinna Saxby +2 more
wiley +1 more source
A Fully Integrated Monolithic Monitor for Aging-Induced Leakage Current Characterization. [PDF]
Darko EN +4 more
europepmc +1 more source
Irish traveller women and sexual assault: Patterns of engagement with sexual assault treatment units
Abstract Objective To detail the attendance of female Irish Travellers at the national Sexual Assault Treatment Unit (SATU) network. Methods Retrospective cross‐sectional study examining the attendance of female patients who identified as members of the Irish Traveller community at the national SATU network between 2017 and 2023 and comparing them with
Daniel Kane +7 more
wiley +1 more source
Convergence and Reducibility as Transferability Filters in Biomimetic Design. [PDF]
Polašek O.
europepmc +1 more source
Abstract Background Intraoperative ureteral injury, although uncommon, can result in significant morbidity and medicolegal consequences, particularly during complex gynecologic procedures such as endometriosis excision and prolapse repair. Conventional ureteral identification techniques, including stents and methylene blue, have recognized limitations.
Victoria Zhang +3 more
wiley +1 more source
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
An operational target trial emulation framework for causal inference using electronic health record data. [PDF]
Wang Y, Li Y, Lin T, Guo Y.
europepmc +1 more source

