Results 181 to 190 of about 3,165,419 (303)

DCD-VMUNet: A Dynamic Multi-Scale and Geometry-Aware Network for Coronary Vessel and Stenosis Segmentation in X-Ray Angiography. [PDF]

Bioengineering (Basel)
Quan Y, Yue H, Ma X, Liu K.
europepmc   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Design and analysis of Low power Rapid Charge Holding Dynamic Latched Comparator [PDF]

Informacije MIDEM
J. V. S. Thirunavukkarasu, P. Kuppusamy   +1 more
doaj   +1 more source

Foot-Targeted Rehabilitation for Pronation-Related Anterior Knee Pain: A Two-Phase Case-Control Study and Single-Blind Randomized Controlled Trial of Manual Therapy Versus Neuromuscular Training Each With Augmented Low-Dye Taping. [PDF]

Physiother Res Int
Anand Udhaya Kumar A, Ramalingam V, Rajendran V.   +2 more
europepmc   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Effects of Resistance Training on Systolic and Diastolic Blood Pressure in Hypertensive Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

J Clin Med
Romero-Vera L, Lara-De la Fuente J, Guede-Rojas F, Carvajal-Parodi C, Araya-Sierralta S, Pérez-Contreras J, Ulloa-Díaz D, Rodríguez-Perea Á.   +7 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Correspondence Concerning 'Aerobic Exercise Plus Hypocaloric Diet on Serum Leptin Concentrations in Adults With Primary Hypertension and Overweight/Obesity: Results From the EXERDIET-HTA Trial'. [PDF]

Clin Obes
Maldonado-Martín S, Corres P, Gorostegi-Anduaga I, Aparicio VA.   +3 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

An Observer-Data-Path Decoupled Time-Domain ADC with Three-Stage Digital Background Calibration in 28 nm CMOS. [PDF]

Micromachines (Basel)
Qin C, Liu B, Wang R, Li L, Zhang C.
europepmc   +1 more source