Results 221 to 230 of about 7,385,916 (287)

Spatial-Temporal Information Fusion for Thyroid Nodule Segmentation in Dynamic Contrast-Enhanced MRI: A Novel Approach. [PDF]

J Imaging Inform Med
Han B, Yang Q, Tao X, Wu M, Yang L, Deng W, Cui W, Luo D, Wan Q, Liu Z, Zhang N.   +10 more
europepmc   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen, Xiaoxiao Chen, Baozhu Yang, Hui Xu, Xueting Sun, Hongkai Qi, Huilin Hu, Ronghua Wu, Fengkai Qiu, Bing Wu, Yu Luo, Gaofeng Shu, Jiansong Ji   +12 more
wiley   +1 more source

Dynamic contrast-enhanced MRI-based radiomics model of intra-tumoral kinetic heterogeneity for predicting breast cancer molecular subtypes. [PDF]

Front Mol Biosci
Cheng Y, Ren R, Xu Y, Duan S, Zhang J, Bao Z.   +5 more
europepmc   +1 more source

Molecular MRI Reveals Macrophage‐Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer

Advanced Science, EarlyView.
Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He, Han Xu, Julian M. M. Rogasch, Nikolaus Berndt, Jing Guo, Eyk Schellenberger, Akvile Häckel, Luisa Heidemann, Friederike Hesse, Yu Liu, Justus Ramtke, Nicola Beindorff, Frank Hofheinz, Avan Kader, Michael Mülleder, Kathrin Textoris‐Taube, Bernd Hamm, Dominik N. Müller, Robin Schmidt, Ralf Hauptmann, Heike Traub, Mathias Schannor, Lynn Jeanette Savic   +22 more
wiley   +1 more source

Publisher Correction: Early-phase semi-quantitative analysis versus full time-course quantitative modeling of ultrafast dynamic contrast-enhanced MRI for breast cancer diagnosis, molecular subtyping, and treatment response prediction. [PDF]

Insights Imaging
Cao Y, Gong X, Huang Y, Chen H, Fang J, Wang L, Li L, Tang S, Yin T, Wang X, Zhang J.   +10 more
europepmc   +1 more source

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

Radiomics analysis based on dynamic contrast-enhanced MRI for predicting early recurrence after hepatectomy in hepatocellular carcinoma patients. [PDF]

Sci Rep
Wang KD, Guan MJ, Bao ZY, Shi ZJ, Tong HH, Xiao ZQ, Liang L, Liu JW, Shen GL.   +8 more
europepmc   +1 more source

Deep Learning for AD Risk Screening and Progression Prediction

Advanced Science, EarlyView.
A pretrained MRI‐based deep learning model generalizes from Western cohorts to an independent Chinese cohort, detects Alzheimer's disease with high sensitivity, and identifies elevated AD risk years before diagnosis. Its risk scores align with cognition and plasma biomarkers, and individualized brain risk maps uncover clinically distinct subtypes ...
Bin Lu, Yan‐Rong Chen, Rui‐Xian Li, Ming‐Kai Zhang, Shao‐Zhen Yan, Guan‐Qun Chen, Jing‐Hua Wang, Wen‐Hui Chai, Francisco Xavier Castellanos, Paul M. Thompson, Jie Lu, Ying Han, Chao‐Gan Yan   +12 more
wiley   +1 more source

<i>In vivo</i> spatiotemporal mapping of proliferation activity in gliomas via water-exchange dynamic contrast-enhanced MRI. [PDF]

Theranostics
Bai R, Jia Y, Wang B, Wang Z, Han G, Liang L, Chen L, Ming Y, Zhu G, Hsu YC, Zhao P, Zhang Y, Liu Z, Liu C, Li Z, Liu Y.   +15 more
europepmc   +1 more source

Early-phase semi-quantitative analysis versus full time-course quantitative modeling of ultrafast dynamic contrast-enhanced MRI for breast cancer diagnosis, molecular subtyping, and treatment response prediction. [PDF]

Insights Imaging
Cao Y, Gong X, Huang Y, Chen H, Fang J, Wang L, Li L, Tang S, Yin T, Wang X, Zhang J.   +10 more
europepmc   +1 more source