Results 151 to 160 of about 12,005,461 (356)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

High-Speed Flight Vehicle Strong Interference Data-Driven Control Based on Self-Organizing Map and Improved Moth-Flame Optimization

Aerospace
Owing to their reliance on detailed mathematical modeling, traditional control methods encounter challenges such as high control complexity and low precision when applied to high-speed flight vehicle control under strongly disturbed atmospheric ...
Chenghao Wang, Kaiqiang Feng, Jie Li, Li Qin, Xi Zhang, Junlong Li, Songhao Zhang, Yanchun Suo   +7 more
doaj   +1 more source

Simultaneous localization and mapping in a multi-robot system in a dynamic environment with unknown initial correspondence. [PDF]

Front Robot AI, 2023
Malakouti-Khah H, Sadeghzadeh-Nokhodberiz N, Montazeri A.   +2 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Deep Regression Model for Tongue Image Color Correction Based on CNN

Journal of Imaging
Different viewing or shooting situations can affect color authenticity and generally lead to visual inconsistencies for the same images. At present, deep learning has gained popularity and opened up new avenues for image processing and optimization.
Xiyuan Cao, Delong Zhang, Chunyang Jin, Wei Zhang, Zhidong Zhang, Chenyang Xue   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Single-Mode Capability Enhancement of Curved Sapphire Fiber Utilizing High-Order Mode Suppression Characteristics Applied at High Temperature

Micromachines
In this paper, a comprehensive investigation into the single-mode capability of curved sapphire fiber is performed, ranging from theoretical simulation to experimental verification.
Fan He, Chengkuo Lee, Xiaojin Zhang, Jiamin Chen, Yongqiu Zheng, Chenyang Xue   +5 more
doaj   +1 more source

Natural plant growth and development achieved in the IPK PhenoSphere by dynamic environment simulation. [PDF]

Nat Commun, 2023
Heuermann MC, Knoch D, Junker A, Altmann T.   +3 more
europepmc   +1 more source

Path planning in dynamic environments.

, 2007
Path planning plays an important role in various fields of application, such as CAD design, computer games and virtual environments, molecular biology, and robotics. In its most general form, the path planning problem is formulated as finding a collision-free path for a moving entity between a start and a goal configuration in an environment containing
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source