Results 131 to 140 of about 8,790,619 (254)

Single-Mode Capability Enhancement of Curved Sapphire Fiber Utilizing High-Order Mode Suppression Characteristics Applied at High Temperature

Micromachines
In this paper, a comprehensive investigation into the single-mode capability of curved sapphire fiber is performed, ranging from theoretical simulation to experimental verification.
Fan He, Chengkuo Lee, Xiaojin Zhang, Jiamin Chen, Yongqiu Zheng, Chenyang Xue   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Kansas environment, 1981

, 1981
This internet resource combines newsletters issued throughout the year.
Kansas. Division of Environment
core   +1 more source

PMT-TC: A Programmable Multi-Event Triggering and Timing Coordination System for Rocket-Sled Ejection Tests

Aerospace
Fixed delays and single-state thresholds are difficult to adapt to dependent event sequences, short authorization windows, and multi-parameter constraints in rocket-sled ejection tests.
Danlu Yin, Dongrui Jiang, Jiachen Yu, Xuanting Liu, Zhiyuan Liu, Huixin Zhang   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Kansas environment, 1980

, 1980
This internet resource combines newsletters issued throughout the year.
Kansas. Division of Environment
core   +1 more source

A TCN-BiLSTM and ANR-IEKF Hybrid Framework for Sustained Vehicle Positioning During GNSS Outages

Sensors
The performance of integrated Global Navigation Satellite System and Inertial Navigation System (GNSS/INS) navigation often declines in complex urban environments due to frequent GNSS signal blockages.
Senhao Niu, Jie Li, Chenjun Hu, Junlong Li, Debiao Zhang, Kaiqiang Feng   +5 more
doaj   +1 more source

Kansas Environment, 1983

, 1983
This internet resource combines newsletters issued throughout the year.
Kansas. Division of Environment
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source