Results 121 to 130 of about 3,607,762 (241)

Search strategy in a complex and dynamic environment: the MH370 case. [PDF]

Sci Rep, 2020
Ivić S, Crnković B, Arbabi H, Loire S, Clary P, Mezić I.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The PRIME-NL study: evaluating a complex healthcare intervention for people with Parkinson's disease in a dynamic environment. [PDF]

BMC Neurol
Maas BR, van den Bergh R, van den Berg SW, Hulstein E, Stadhouders N, Jeurissen PPT, de Vries NM, Bloem BR, Munneke M, Ben-Shlomo Y, Darweesh SKL.   +10 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Path planning of mobile robot based on improved TD3 algorithm in dynamic environment. [PDF]

Heliyon
Li P, Chen D, Wang Y, Zhang L, Zhao S.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

DSOMF: A Dynamic Environment Simultaneous Localization and Mapping Technique Based on Machine Learning. [PDF]

Sensors (Basel)
Yue S, Wang Z, Zhang X.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Real-time Trajectory Planning and Tracking Control of Bionic Underwater Robot in Dynamic Environment. [PDF]

Cyborg Bionic Syst
Ding F, Wang R, Zhang T, Zheng G, Wu Z, Wang S.   +5 more
europepmc   +1 more source

Thermography methods to assess stomatal behaviour in a dynamic environment. [PDF]

J Exp Bot, 2020
Vialet-Chabrand S, Lawson T.
europepmc   +1 more source