Results 121 to 130 of about 8,790,619 (254)

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Interaction of dynamic indoor environment with moving person and performance of ceiling mounted personalized ventilation system

open access: yes, 2013
Ceiling mounted personalized ventilation (PV) aims to provide clean outdoor air into human breathing zone without affecting indoor aesthetics in energy-efficient manner.
Sekhar, Chandra,, Yang, Bin,
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Coming to know about 'dependency' within a dynamic geometry environment

open access: yes, 1996
The ability to define relationships between objects is one of the most powerful features of a dynamic geometry package such as Cabri-Géomètre. In this paper I document how one pair of 12 year old students begin to come to know about this form of ...
Jones, Keith
core   +1 more source

High-Speed Flight Vehicle Strong Interference Data-Driven Control Based on Self-Organizing Map and Improved Moth-Flame Optimization

open access: yesAerospace
Owing to their reliance on detailed mathematical modeling, traditional control methods encounter challenges such as high control complexity and low precision when applied to high-speed flight vehicle control under strongly disturbed atmospheric ...
Chenghao Wang   +7 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Underground coal-rock image recognition using Swin-UNet with agent attention mechanism

open access: yesMeitan kexue jishu
To address the challenges of coal-rock image segmentation under complex underground mining conditions—such as low illumination, high noise, and motion blur—this paper proposes an improved semantic segmentation model named Agent Swin-UNet, which ...
Chuanmeng SUN   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Deep Regression Model for Tongue Image Color Correction Based on CNN

open access: yesJournal of Imaging
Different viewing or shooting situations can affect color authenticity and generally lead to visual inconsistencies for the same images. At present, deep learning has gained popularity and opened up new avenues for image processing and optimization.
Xiyuan Cao   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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