Results 111 to 120 of about 1,736,262 (298)

Triggered memory-based swarm optimization in dynamic environments [PDF]

This is a post-print version of this article - Copyright @ 2007 Springer-VerlagIn recent years, there has been an increasing concern from the evolutionary computation community on dynamic optimization problems since many real-world optimization problems ...
D. Parrott, J. Branke, J. Branke, J. Kennedy, R. Eberhart, R. Eberhart, R.W. Morrison, S. Yang, T. Blackwell, X. Hu   +9 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

A Time-Aware Routing Map for Indoor Evacuation

Sensors, 2016
Knowledge of dynamic environments expires over time. Thus, using static maps of the environment for decision making is problematic, especially in emergency situations, such as evacuations.
Haifeng Zhao, Stephan Winter
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Learning to Cooperate via an Attention-Based Communication Neural Network in Decentralized Multi-Robot Exploration

Entropy, 2019
In a decentralized multi-robot exploration problem, the robots have to cooperate effectively to map a strange environment as soon as possible without a centralized controller.
Mingyang Geng, Kele Xu, Xing Zhou, Bo Ding, Huaimin Wang, Lei Zhang   +5 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Random Feature-based Online Multi-kernel Learning in Environments with Unknown Dynamics [PDF]

, 2018
Kernel-based methods exhibit well-documented performance in various nonlinear learning tasks. Most of them rely on a preselected kernel, whose prudent choice presumes task-specific prior information.
Chen, Tianyi, Giannakis, Georgios B., Shen, Yanning   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

YSAG-VINS—A Robust Visual-Inertial Navigation System with Adaptive Geometric Constraints and Semantic Information Based on YOLOv8n-ODUIB in Dynamic Environments

Applied Sciences
Dynamic environments pose significant challenges for Visual Simultaneous Localization and Mapping (VSLAM), as moving objects can introduce outlier observations that severely degrade localization and mapping performance.
Kunlin Wang, Dashuai Chai, Xiqi Wang, Ruijie Yan, Yipeng Ning, Wengang Sang, Shengli Wang   +6 more
doaj   +1 more source