Results 91 to 100 of about 4,421,442 (301)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Simple method to the dynamic modeling of industrial robot subject to constraint

open access: yesAdvances in Mechanical Engineering, 2016
It is a common movement type in industrial production for the end-effector of industrial robot executing tasks according to desired track. High nonlinearity and coupling are shown from the dynamic characteristic of industrial robot because of the ...
Jia Liu, Rong Liu
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Effects of Regional Trade Agreements Using a Static and Dynamic Gravity Equation [PDF]

open access: yes
This paper evaluates the static effects of preferential agreements between several economic blocs and areas using a dynamic gravity equation. The main aim is to investigate whether regionalism has fostered intra or/and extra blocs international trade ...
Felicitas Nowak-Lehmann D.   +2 more
core  

Balancing control of unicycle robot by using sliding control

open access: yesJournal of Measurement Science and Instrumentation, 2012
This paper discusses about balancing control of unicycle robot.Unicycle robot consists of pitch which acts like inverted pendulum and roll which acts like reaction wheel pendulum.The robot which does not have actuator located in yaw axis is made to ...
Inwoo Han   +3 more
doaj  

Calculating Lyapunov Value for the Logistic Equation with Rapidly Oscillating Delay

open access: yesМоделирование и анализ информационных систем, 2014
We consider the local dynamic of the logistic equation with rapidly oscillating timeperiodic piecewise constant or piecewise linear coefficient of delay.
N. D. Bykova
doaj   +1 more source

Dynamics of the semiclassical Einstein equations

open access: yesPhysical Review D, 1986
An investigation is done on the behavior of the Einstein equation for the case of a conformally invariant field in a conformally flat spacetime when higher-order derivative terms with logarithmic dependence on the scalar curvature are introduced. It is seen that in the quantum case, flat spacetime is always stable to conformally flat perturbations ...
openaire   +3 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Dynamic modelling of a fractionation process for a liquid mixture using supercritical carbon dioxide [PDF]

open access: yes, 2001
This work presents a simple dynamic modelling of a process of separation of a quaternary mixture using supercritical CO2. Thermodynamic description is accomplished using efficient available models (SRK equation of state with MHV2 mixing rules).
Camy, Séverine   +3 more
core   +1 more source

Sequential action and beliefs under partially observable DSGE environments [PDF]

open access: yes, 2012
Revised and resubmitted at Computational EconomicsThis paper introduces a classification of DSGEs from a Markovian perspective, and positions the class of POMDP (Partially Observable Markov Decision Process) to the center of a generalization of linear ...
Kim, Seong-Hoon
core   +1 more source

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