Results 91 to 100 of about 2,008,509 (298)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Necessary Condition for an Euler-Lagrange Equation on Time Scales

Abstract and Applied Analysis, 2014
We prove a necessary condition for a dynamic integrodifferential equation to be an Euler-Lagrange equation. New and interesting results for the discrete and quantum calculus are obtained as particular cases. An example of a second order dynamic equation,
Monika Dryl, Delfim F. M. Torres
doaj   +1 more source

Non-Markovian Relaxation of a Three-Level System: Quantum Trajectory Approach

, 2010
The non-Markovian dynamics of a three-level quantum system coupled to a bosonic environment is a difficult problem due to the lack of an exact dynamic equation such as a master equation.
H. Carmichael, H. P. Breuer, Jun Jing, Ting Yu   +3 more
core   +1 more source

Dynamics of Nonlinear Wave Equations [PDF]

, 2019
80pages. This lecture was written for LIASFMA School on Harmonic Analysis and Wave Equations in Fudan universty(2017). arXiv admin note: text overlap with arXiv:1506.00788, arXiv:0710.5934, arXiv:1407.4525, arXiv:1601.01871, arXiv:1301.4835, 1509.03331, arXiv:1010.3799, arXiv:1201.3258, arXiv:0911.4534, arXiv:1411.7905, by other ...
Miao, Changxing, Zheng, Jiqiang
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Qualitative analysis on existence and stability of nonlinear fractional dynamic equations on time scales

Nonlinear Engineering
This study explores the qualitative analysis of Dγh(ζ)=ℒ(ζ,h(ζ),Dγh(ζ)),\begin{array}{r}{{\mathcal{D}}}^{\gamma }{\mathfrak{h}}\left(\zeta )={\mathcal{ {\mathcal L} }}\left(\zeta ,{\mathfrak{h}}\left(\zeta ),{{\mathcal{D}}}^{\gamma }{\mathfrak{h}}\left ...
Nisar Kottakkaran Sooppy, Anusha Chandran, Ravichandran Chokkalingam, Sabarinathan Sriramulu   +3 more
doaj   +1 more source

Selection-endogenous ordered probit and dynamic ordered probit models [PDF]

In this presentation we define two qualitatitive response models: 1) Selection Endogenous Dummy Ordered Probit model (SED-OP); 2) a Selection Endogenous Dummy Dynamic Selection Ordered Probit model (SED- DOP).
Alfonso Miranda, Massimiliano Bratti
core  

Global solution to the Allen-Cahn equation with singular potentials and dynamic boundary conditions

, 2012
We prove well-posedness results for the solution to an initial and boundary-value problem for an Allen-Cahn type equation describing the phenomenon of phase transitions for a material contained in a bounded and regular domain.
Allen, Barbu, Barbu, Brezzi, Brokate, Brézis, Caginalp, Cahn, Chill, Elliott, Escher, Feng, Fischer, Gal, Gal, Gilardi, Grasselli, Grasselli, Kenzler, Lions, Luca Calatroni, Miranville, Pierluigi Colli, Schimperna, Simon, Sprekels, Wheeler   +26 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

On the boomerang flight path

Известия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. The study proposes an algorithm for deriving equations of dynamics in the case of complex three-dimensional motion of bodies which is demonstrated by a specific example of the flight of a boomerang, which indicates the relevance of the study,
Sergey O. Gladkov
doaj   +1 more source