Results 101 to 110 of about 835,866 (315)
Dynamic methods of air traffic flow management [PDF]
Transport Problems, 2011 Air traffic management is a complex hierarchical system. Hierarchy levels can be defined according to decision making time horizon or to analyze area volume.
Jacek SKORUPSKI
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Velocity Measurements Ahead of a Semi-Infinite Body in Magnetohydrodynamic Flow with Aligned Fields [PDF]
, 1969 NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document. Experiments are described in which velocities were measured ahead of a semi-infinite Rankine body moving parallel to a uniform magnetic ...
Lake, Bruce Meno
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Analysis of dynamic system optimum and externalities with departure time choice
, 2006 This paper aims to analyse the dynamic system optimal assignment with departure time choice, which is an important, yet underdeveloped area. The main contribution of this paper is the necessary conditions and the sensitivity analysis for dynamic system
Chow, A.H.F.
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Studying the Factors Affecting the Settling Velocity of Solid Particles in Non-Newtonian Fluids
مجلة النهرين للعلوم الهندسية, 2017 The aim of this research is to study the factors affecting the settling velocity (V S ) in Non-Newtonian fluids which are the rheological properties, concentrations of non-Newtonian fluids, particle shape and size.
Muhanned A.R. Mohammed +1 more
doaj
A Lagrangian discretization multiagent approach for large-scale multimodal dynamic assignment [PDF]
This paper develops a Lagrangian discretization multiagent model for large-scale multimodal simulation and assignment. For road traffic flow modeling, we describe the dynamics of vehicle packets based on a macroscopic model on the basis of a Lagrangian ...
Jean-Patrick Lebacque, Tai-Yu Ma
core