Results 111 to 120 of about 835,866 (315)

Active control of hydrodynamic slug flow [PDF]

, 2013
Multiphase flow is associated with concurrent flow of more than one phase (gas-liquid, liquid-solid, or gas-liquid-solid) in a conduit. The simultaneous flow of these phases in a flow line, may initiate a slug flow in the pipeline. Hydrodynamic slug flow
Inyiama, Fidelis Chidozie
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Two-phase flow experimental studies in micro-models

, 2013
The aim of this research project was to put more physics into theories of two-phase flow. The significance of including interfacial area as a separate variable in two-phase flow and transport models was investigated.
Physically-based theory of two-phase flow in porous media including fluid-fluid interfacial area, Hydrogeology, Karadimitriou, N.K.   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Hierarchical fluctuation shapes a dynamic flow linked to states of consciousness. [PDF]

Nat Commun, 2023
Li A, Liu H, Lei X, He Y, Wu Q, Yan Y, Zhou X, Tian X, Peng Y, Huang S, Li K, Wang M, Sun Y, Yan H, Zhang C, He S, Han R, Wang X, Liu B.   +18 more
europepmc   +1 more source

Hybrid Estimation of Inflow Multiphase Production Rates Using a Dynamic Wellbore Flow Model

This paper considers the problem of estimating the quantitative parameters of a two-phase fluid flow in a well based on the dynamic physical flow model.
Muhammad Arsalan, Eugene Magadeev, Andrey Kovalskii, Anton Gryzlov   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Coordination of Hydropower Generation and Export Considering River Flow Evolution Process of Cascade Hydropower Systems

Energies
Focusing the over simplification of existing models in simulating river flow evolution process and lack of coordination of hydropower generation and export, this paper proposes a hydropower generation and export coordinated optimal operation model that ...
Pai Li, Hui Lu, Lu Nan, Jiayi Liu
doaj   +1 more source

In Vitro Thrombogenicity Testing of Biomaterials in a Dynamic Flow Loop: Effects of Length and Quantity of Test Samples. [PDF]

J Med Device, 2023
Jamiolkowski MA, Golding MD, Malinauskas RA, Lu Q.   +3 more
europepmc   +1 more source