Results 131 to 140 of about 835,866 (315)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The Usefulness of MRI Dynamic Flow Sequences in Differentiating High- and Low-Flow Vascular Malformations. [PDF]
J Clin Med, 2022 Majewska NK +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Dynamic process of the “8•31” debris flow in Luoxi gulley of Ganluo County, Sichuan Province
Zhongguo dizhi zaihai yu fangzhi xuebaoHeixiluo gully, located in Suxiong Town, Ganluo County of Sichuan Province, experienced a catastrophic debris flow disaster at 8:00 a.m. on August 31, 2020, causing significant losses to local residents, as well as to the Chengdu–Kunming railway bridges ...
Jishuai SHI +2 more
doaj +1 more source
A dynamic flow model mimicking duodenoscope reprocessing after bacterial contamination for translational research. [PDF]
Antimicrob Steward Healthc Epidemiol, 2022 Heuvelmans M +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
An Automated Jet Nebulizer with Dynamic Flow Regulation. [PDF]
J Pharm Innov, 2022 Dampage U, Ariyasinghe M, Pulleperuma S.
europepmc +1 more source
"A Simplified 'Benchmark” Stock-flow Consistent (SFC) Post-Keynesian Growth Model" [PDF]
Despite being arguably one of the most active areas of research in heterodox macroeconomics, the study of the dynamic properties of stock-flow consistent (SFC) growth models of financially sophisticated economies is still in its early stages.
Gennaro Zezza, Claudio H. Dos Santos
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Dynamic compliance in flow-controlled ventilation
Intensive Care Medicine Experimental, 2021 Dietmar Enk +3 more
doaj +1 more source