Results 101 to 110 of about 983,585 (327)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

"Warm Bodies": A Post-Processing Technique for Animating Dynamic Blood Flow on Photos and Avatars [PDF]

, 2021
Daniel McDuff, Ewa M. Nowara
openalex   +1 more source

A study of fluid dynamics of gaseous nuclear rockets Quarterly progress report, period ending Jun. 30, 1968 [PDF]

Bibliography on vortex flows for fluid dynamic containment of gaseous nuclear rocket ...
Lewellen, W. S.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Using a tracer technique to identify the extent of non-ideal flows in the continuous mixing of non-Newtonian fluids

EPJ Web of Conferences, 2013
The identification of non-ideal flows in a continuous-flow mixing of non-Newtonian fluids is a challenging task for various chemical industries: plastic manufacturing, water and wastewater treatment, and pulp and paper manufacturing. Non-ideal flows such
Mehrvar M., Ein-Mozaffari F., Patel D.
doaj   +1 more source

Intervertebral Disc‐on‐a‐Chip^MF: A New Model for Mouse Disc Culture via Integrating Mechanical Loading and Dynamic Media Flow (Adv. Mater. Technol. 21/2023) [PDF]

, 2023
Wanqing Xie, Yuan Xing, Li Xiao, Pu Zhang, Richard Oh, Yangpu Zhang, Xiaoyu Yu, Ying He, Eunha Oh, Ruofan Cao, Melur K. Ramasubramanian, Yong Wang, Jin Li, Jose Oberhozler, Xudong Li   +14 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Failure mechanism and dynamic process of landslide triggered debris flows—an example from Chongqing, China

Frontiers in Earth Science
Shallow landslides and debris flows triggered by heavy rainfall are widespread catastrophic geological disasters in mountainous areas. Landslides with complex terrain are often the material source of debris flows as a disaster chain. However, the failure
Fen Wang, Fen Wang, Zhenwei Dai, Anle Zhang, Anle Zhang, Shi Cheng, Shi Cheng, Qihui Xiong   +7 more
doaj   +1 more source

Progesterone Alters Biliary Flow Dynamics

Annals of Surgery, 1999
To test the hypothesis that progesterone alters sphincter of Oddi and gallbladder function and, therefore, bile flow dynamics.Although the effects of progesterone on the biliary tract have been implicated in the increased incidence of gallstones among women, the specific effects of prolonged elevation of progesterone levels, such as occurs with ...
S, Tierney, A, Nakeeb, O, Wong, P A, Lipsett, S, Sostre, H A, Pitt, K D, Lillemoe   +6 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source