Results 131 to 140 of about 983,585 (327)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Primary mechanism of stroke reduction in transcarotid artery revascularization is dynamic flow reversal [PDF]
, 2020 Isaac Naazie +5 more
openalex +1 more source
Valuing future cash flows with non separable discount factors and non additive subjective measures: Conditional Choquet Capacities on Time and on Uncertainty [PDF]
We consider future cash flows that are contingent both on dates in time and on uncertain states. The decision maker (DM) values the cash flows according to its decision criterion: Here the payoffs’ expectation with respect to a capacity measure.
André Lapied, Robert Kast
core
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
CARE TRANSITIONS: DYNAMIC INTERACTION AND INFORMATION FLOW [PDF]
, 2016 Greta G. Cummings +6 more
openalex +1 more source
The Potential of Foreign Aid as Insurance [PDF]
This paper quantifies the potential of foreign aid as an insurance mechanism against macroeconomic shocks. Within a dynamic model of aid flows between two endowment economies, we show that at least three-fourths of the large welfare costs of ...
Catherine Bérubé +2 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Dynamic computed tomographic imaging of regional cerebral blood flow and blood volume. A clinical pilot study. [PDF]
, 1993 Hans Jakob Steiger +2 more
openalex +1 more source
Fast solutions to the steady state compressible and incompressible fluid dynamic equations [PDF]
For low speed flows the use of the compressible fluid dynamic equations is inefficient. The use of an explicit scheme requires delta t to be bounded by 1/c. However, the physical parameters change over time scales of order 1/u which is much larger. Hence,
Turkel, E.
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source