Results 41 to 50 of about 72,806 (265)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

ACCOUNTING INFLUENCE OF CENTRIFUGAL FORCE IN THE NUMERICAL MODELING OF RISING SWIRLED GAS FLOW

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2015
In work the consistent inclusion of centrifugal force in the numerical calculations of three-dimensional gas-dynamic characteristics of the unsteady flow of compressible viscous heat-conducting gas in an upward swirling flow caused by the vertical cold ...
S. P. Bautin, A. G. Obukhov
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Dynamic Flow-Assisted Nanoarchitectonics

open access: yesACS Applied Materials & Interfaces
The solution to societal problems such as energy, environmental, and biomedical issues lies in the development of functional material systems with the capacity to address these problems. In the course of human development, we are entering a new era in which nanostructure control is considered in the major development of functional materials.
Katsuhiko Ariga   +2 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Dynamic Modeling for Metro Passenger Flows on Congested Transfer Routes

open access: yesMathematics, 2023
With the rapid development of urbanization, the metro becomes more and more important for people’s travel in big cities. To quantitatively describe metro passenger flows on congested transfer routes, this paper introduces a dynamic model based on ...
Weiyan Mu   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Dynamic Electroosmotic Flows of Power-Law Fluids in Rectangular Microchannels

open access: yesMicromachines, 2017
Dynamic characteristics of electroosmosis of a typical non-Newtonian liquid in a rectangular microchannel are investigated by using numerical simulations.
Cunlu Zhao, Wenyao Zhang, Chun Yang
doaj   +1 more source

ARBITRARY INTERACTION OF PLANE SUPERSONIC FLOWS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2015
Subject of study.We consider the Riemann problem for parameters at collision of two plane flows at a certain angle. The problem is solved in the exact statement.
P. V. Bulat, K. N. Volkov
doaj   +1 more source

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