Results 61 to 70 of about 75,918 (267)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
ReMatching Dynamic Reconstruction Flow
CoRROur project website is at https://research.nvidia.com/labs/toronto-ai ...
Sara Oblak +3 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Time Can Flow in the Opposite Direction of What We Think It Does
ProblemosAttitudes towards the future and the past differ. This difference seems easy to explain if time actually flows, and thus, has an intrinsic direction. At first, this appears to be an advantage of the dynamic view of time, according to which time really ...
Kunihisa Morita
doaj +1 more source
Dynamic migration flow modeling
Security Dialogues /Безбедносни дијалози, 2017 The paper presents a SD model that analyses migrant/refugee flow, taking into account the following parameters: political decisions of the countries on migrant routes (political intervention), socio-economic factors, the porosity of state borders, criminal activities, public opinion, health, climate, and environmental conditions, etc.
Vladimir Ninković +2 more
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Dynamic ultrasonic visualization of blood vessels and flows
Archives of Acoustics, 2016 This paper describes a new method for dynamic real-time visualization of blood flows. This method uses a special signal processing system (SEC) which consists in cancellation of stationary echoes from the reflections of ultrasonic waves from soft tissues
Andrzej NOWICKI, John M. REID
doaj