Results 41 to 50 of about 75,918 (267)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Dynamics of Capital Flow Episodes [PDF]

open access: yesJournal of Money, Credit and Banking, 2019
AbstractWe first propose a novel methodology for identifying episodes of strong equity and bond flows using estimates from a regime‐switching model that keeps context‐ and sample‐specific assumptions to a minimum. We then assess the impacts of U.S. stock market volatility (VIX) and U.S. monetary policy shocks on equity and bond flow episodes.
Friedrich, Christian, Guérin, Pierre
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Foundations of Engineering Mathematics Applied for Fluid Flows

open access: yesAxioms, 2021
Based on a brief historical excursion, a list of principles is formulated which substantiates the choice of axioms and methods for studying nature. The axiomatics of fluid flows are based on conservation laws in the frames of engineering mathematics and ...
Yuli D. Chashechkin
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Welfare Flows and Caseload Dynamics [PDF]

open access: yesJournal of Applied Economics, 2007
Data from the 1990, 1991, 1992, 1993 and 1996 panels of the Survey of Income and Program Participations are used to estimate AFDC/TANF entry and exit rates. These estimates of AFDC/TANF entry and exit rates are used to conduct simulations aimed at determining the roles of economic conditions and welfare reform in explaining AFDC caseloads changes ...
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SIMULATION OF CONTROL PROCESSES OF PROJECTS’ RESOURCE FLOWS

open access: yesВісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2015
The features of the control resource flows projects and programs are considered. The agent-based simulation model of dynamic analysis of resource management processes in implementation of the enterprise project portfolio, which considers a number of ...
Сергей Геннадиевич КИЙКО
doaj   +1 more source

[Advanced Dynamic Flow]

open access: yesIgaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2001
There are problems for contrast imaging using LevovistTM contrast agent. In case of Doppler mode, poor resolution and large blooming area are the problems. In case of 2nd harmonic imaging and pulse inversion imaging, tissue harmonic image(THI) becomes the problem because Levovist needs high mechanical index(MI).
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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