Results 51 to 60 of about 423,780 (329)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Holistic Measurement of the Friction Behavior of Wet Clutches
LubricantsThe safe and efficient torque transmission of wet disk clutch systems requires high coefficients of friction. To achieve good controllability and high comfort, a positive slope of the coefficient of friction over sliding velocity is ensured by a ...
Patrick Strobl +5 more
doaj +1 more source
Tribology Online, 2012 In this research, dynamic friction behavior of paper-based wet friction material subjected to contact pressure fluctuation was investigated experimentally and theoretically. Complex friction coefficient obtained by the ratio between dynamic components of
Yasuhisa Hattori, Yusuke Kato
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Scanning-electron-microscope used in real-time study of friction and wear [PDF]
, 1975 Small friction and wear apparatus built directly into scanning-electron-microscope provides both dynamic observation and microscopic view of wear process.
Brainard, W. A., Buckley, D. H.
core +1 more source
Methods of calculation of a friction coefficient: Application to the nanotubes
, 2003 In this work we develop theoretical and numerical methods of calculation of a dynamic friction coefficient. The theoretical method is based on an adiabatic approximation which allows us to express the dynamic friction coefficient in terms of the time ...
H. Goldstein +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
eXPRESS Polymer Letters, 2010 Nanocomposites of PMMA+MMT Brazilian clays were developed by mechanical mixing in co-rotational twinscrew extrusion and injection molding with varying weight fraction of MMT Brazilian clays.
doaj +1 more source
Concrete-to-concrete shear friction behavior under cyclic loading: experimental investigation
Scientific Reports, 2022 This study investigated the concrete-to-concrete friction behavior under dynamic cyclic loading at different loading rates, vertical loads, and surface roughness.
Mohamad Taklas +4 more
doaj +1 more source