Results 171 to 180 of about 12,139,664 (308)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Estimating economic impact using ex post econometric analysis: Cautionary tales [PDF]

This paper provides an overview of techniques that can be used to estimate the economic impact of stadiums, events, championships, and franchises on local economies.
Robert Baumann, Victor Matheson
core   +2 more sources

Static Disorder has Dynamic Impact on Energy Transport in Biomimetic Light-Harvesting Complexes. [PDF]

J Phys Chem B, 2022
Hamerlynck LM, Bischoff AJ, Rogers JR, Roberts TD, Dai J, Geissler PL, Francis MB, Ginsberg NS.   +7 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Stakeholder Mapping Guide

This resource is a (non-exhaustive) collection of materials on stakeholder mapping, analysis, and engagement, based on the experiences and insights of the Evaluating Societal Impact team.
Evaluating Societal Impact
core   +1 more source

Dynamic Impact of Technology and Finance on Green Technology Innovation Efficiency: Empirical Evidence from China's Provinces. [PDF]

Int J Environ Res Public Health, 2022
Liu Y, Yang Y, Zheng S, Xiao L, Gao H, Lu H.   +5 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Bioengineering approaches to dynamic impact analysis for cranial fracture interpretation in arcaheology. [PDF]

Sci Rep
Rodríguez-Iglesias D, Pantoja-Pérez A, De La Rosa Á, Latorre-Carmona P, Sala N.   +4 more
europepmc   +1 more source

Investigation of Dynamic Impact Responses of Layered Polymer-Graphene Nanocomposite Films Using Coarse-Grained Molecular Dynamics Simulations. [PDF]

Carbon N Y, 2023
Yang Z, Chiang CC, Meng Z.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source