Results 71 to 80 of about 34,236 (270)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

On Nonlanding Dynamic Rays of Exponential Maps

, 2007
We consider the case of an exponential map for which the singular value is accessible from the set of escaping points. We show that there are dynamic rays of which do not land.
Rempe, Lasse
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

GLMI: An Efficient Spatiotemporal Index Leveraging Geohash and Piecewise Linear Models for Optimized Query Performance

Algorithms
Spatiotemporal big data contain information in multiple dimensions such as space and time. Spatiotemporal data have the characteristics of large volume, intricate spatiotemporal relationship, and uneven spatiotemporal distribution. Index structure is one
Kun Chen, Gang Liu, Genshen Chen, Zhengping Weng, Qiyu Chen   +4 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

The Path of the Bicycle. Reflections on the Sense, Achievements and Challenges of the Iberoamerican Summits [PDF]

Revista CIDOB d'Afers Internacionals, 2000
In responding to the question of the meaning and the sense of the Iberoamerican Summits in the international community of the post-cold war period, their achievements and future challenges with particular attention to their implications for Spanish ...
Manuel Montobbio
doaj  

Laser Powder Bed Fusion of Alumina: Effects of Scanning Strategies on External and Internal Defects

Advanced Engineering Materials, EarlyView.
This study investigates how scanning strategies affect pure alumina in laser powder bed fusion. Linear 45° scanning yields uniform surfaces but high porosity, while the island‐concentric strategy provides higher density with through‐holes favorable for infiltration. Findings highlight pathways toward optimizing defect‐free alumina parts.
Mohamed Abdelmoula, Gökhan Küçüktürk, Duran Kaya, David Grossin, Christophe Tenailleau, Benjamin Duployer, Enrique Juste, Fabrice Petit   +7 more
wiley   +1 more source

Mandarin Peels-Derived Carbon Dots: A Multifaceted Fluorescent Probe for Cu(II) Detection in Tap and Drinking Water Samples

Nanomaterials
Carbon dots (CDs) derived from mandarin peel biochar (MBC) at different pyrolysis temperatures (200, 400, 600, and 800 °C) have been synthesized and characterized.
Marwa El-Azazy, Alaa AlReyashi, Khalid Al-Saad, Nessreen Al-Hashimi, Mohammad A. Al-Ghouti, Mohamed F. Shibl, Abdulrahman Alahzm, Ahmed S. El-Shafie   +7 more
doaj   +1 more source

Into the Wild, un prodotto (cine)turistico nordamericano / “Into the Wild”, a North America (cine)touristic product

Il Capitale Culturale: Studies on the Value of Cultural Heritage, 2016
Com’è noto, il turismo si presenta come uno tra i fenomeni territoriali più dinamici e con un’elevata propensione al cambiamento. Negli ultimi decenni, nel mercato si sono imposte nuove forme di turismo con l’obiettivo di soddisfare nuove esigenze dei ...
Caterina Cirelli, Enrico Nicosia, Carmelo Maria Porto   +2 more
doaj   +1 more source