Results 61 to 70 of about 34,236 (270)

Oriented Percolation in One-Dimensional 1/|x-y|^2 Percolation Models

, 2010
We consider independent edge percolation models on Z, with edge occupation probabilities p_ = p if |x-y| = 1, 1 - exp{- beta / |x-y|^2} otherwise. We prove that oriented percolation occurs when beta > 1 provided p is chosen sufficiently close to 1 ...
A. Johansson, A. Klein, C.M. Fortuin, C.M. Fortuin, C.M. Newman, D. H. U. Marchetti, D.H.U. Marchetti, G. Grimmett, G. Grimmett, J. Fröhlich, J. Fröhlich, J.Z. Imbrie, M. Aizenman, M. Aizenman, M. E. Vares, V. Sidoravicius   +15 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Methodology for Engineering Collaborative and ad-hoc Mobile Applications using SyD Middleware [PDF]

, 2010
Today’s web applications are more collaborative and utilize standard and ubiquitous Internet protocols. We have earlier developed System on Mobile Devices (SyD) middleware to rapidly develop and deploy collaborative applications over heterogeneous and ...
Balasooriya, Janaka, Bourgeois, Anu, Hariharan, Arthi, Madiraju, Praveen, Malladi, Srilaxmi, Prasad, Sushil K.   +5 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Performing Hybrid Recommendation in Intermodal Transportation – the FTMarket System’s Recommendation Module [PDF]

, 2009
Diverse recommendation techniques have been already proposed and encapsulated into several e-business applications, aiming to perform a more accurate evaluation of the existing information and accordingly augment the assistance provided to the users ...
Lazanas, Alexis
core   +1 more source

A Lightweight and Flexible Mobile Agent Platform Tailored to Management Applications

, 2011
Mobile Agents (MAs) represent a distributed computing technology that promises to address the scalability problems of centralized network management. A critical issue that will affect the wider adoption of MA paradigm in management applications is the ...
Gavalas, Damianos
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A multi model orchestrated agent for live flight and hotel itinerary generation

Discover Artificial Intelligence
The evolution of large language models into autonomous, goal-oriented systems capable of advanced reasoning, contextual memory recall, and dynamic tool orchestration is referred to as agentic AI. This work introduces an intelligent travel companion built
B. Nethravathi, Pooja Gupta, C. P. Lalitha Shree, S. Srivatsa, G. N. Harshith, Sudharani   +5 more
doaj   +1 more source

A Multi-Agent Approach for Reactionary Delay Prediction of Flights

IEEE Access, 2019
Flight schedules are highly sensitive to delays and witness these events on a very frequent basis. In an interconnected and interdependent air transportation system, these delays can magnify and cascade as the flight itineraries progress, causing ...
Yash Guleria, Qing Cai, Sameer Alam, Lishuai Li   +3 more
doaj   +1 more source

Designing a Travel Guide to the Un-Natural World: Exploring a Design-led Methodology [PDF]

, 2009
The analogy of designer as tourist in the un-natural world is used as an aid for thinking my way into the nature of design research. An exploration of how the design researcher, like a tourist, travels widely through the un-natural world of thought ...
Hocking, Viveka Turnbull
core