Results 61 to 70 of about 7,121,089 (359)
Numerical Analysis of Roadway Rock-Burst Hazard Under Superposed Dynamic and Static Loads
Energies, 2019 Microseismic events commonly occur during the excavation of long wall panels and often cause rock-burst accidents when the roadway is influenced by dynamic loads.
P. Kong +5 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Механика машин, механизмов и материалов, 2017 The issues associated with determination of dynamic loads encountered in moving the nodes of the planetary mill with a belt drive are considered. The analysis of the influence of constructive and technological parameters on their size is carried out. For
P.E. Vaitekhovich +3 more
doaj
RoboticsThis study proposes an approach to 3D modeling of spatial manipulators in the Maple 2023 software environment. Algorithms and program codes have been developed to create computer 3D models of manipulators controlled by generalized coordinates.
Muratulla Utenov +6 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Employing finite element analysis for assessing the condition monitoring of sandwich beams [PDF]
MATEC Web of ConferencesIn engineering and transportation, beams are frequently utilized as structural elements for both static and dynamic loads. This paper focuses on a smart structure method that incorporates ANSYS software for modeling and simulation.
Asif Kattimani Mohammed +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Dynamic buckling of an inextensible elastic ring: Linear and nonlinear analyses
, 2020 Slender elastic objects such as a column tend to buckle under loads. While static buckling is well understood as a bifurcation problem, the evolution of shapes during dynamic buckling is much harder to study.
Goriely, Alain +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source