Results 71 to 80 of about 1,069,040 (297)

Baseline and long-term frailty transitions and rapid estimated glomerular filtration rate decline: evidence from two large population-based studies

open access: yesRenal Failure
Frailty is widely recognized to be associated with kidney function decline, but its longitudinal relationship with rapid estimated glomerular filtration rate (eGFR) decline remains unclear.
Ying Deng   +8 more
doaj   +1 more source

The dynamic nature of autophagy in cancer [PDF]

open access: yesGenes & Development, 2011
Macroautophagy (referred to hereafter as autophagy) is a highly regulated cellular process that serves to remove damaged proteins and organelles from the cell. Autophagy contributes to an array of normal and pathological processes, and has recently emerged as a key regulator of multiple aspects of cancer biology.
openaire   +2 more sources

The Dynamic Nature of the Nuclear Envelope [PDF]

open access: yesCurrent Biology, 2018
Eukaryotes characteristically organize their genome in a separate compartment, the nucleus, which is surrounded by the nuclear envelope as a barrier. Ruptures of the nuclear envelope and exposure of chromatin threaten cell viability and cause genome instability.
Paola De Magistris, Wolfram Antonin
openaire   +2 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Stability in flux: Community structure in dynamic networks [PDF]

open access: yes, 2010
The structure of many biological, social and technological systems can usefully be described in terms of complex networks. Although often portrayed as fixed in time, such networks are inherently dynamic, as the edges that join nodes are cut and rewired ...
Jansen, Vincent AA   +15 more
core   +1 more source

Dynamic structure of active sites in ceria-supported Pt catalysts for the water gas shift reaction [PDF]

open access: yes, 2021
Oxide-supported noble metal catalysts have been extensively studied for decades for the water gas shift (WGS) reaction, a catalytic transformation central to a host of large volume processes that variously utilize or produce hydrogen.
Vincent, Joshua L.,   +11 more
core   +1 more source

Changes in Frailty and Incident Cancer: Evidence From the Health and Retirement Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Although frailty has been identified as a potential risk factor for cancer, most previous studies have only considered frailty status at a single time point.
Zhaoting Bu   +10 more
doaj   +1 more source

Reviving lost shadows: investigating the habitat ecology of the rediscovered hispid hare (Caprolagus hispidus) in Nepal [PDF]

open access: yesPeerJ
The endangered hispid hare (Caprolagus hispidus) is one of the least studied mammal species. The recent rediscovery of hispid hare in Chitwan National Park (CNP) after three decades, necessitated urgent conservation measures.
Aakriti Prasai   +8 more
doaj   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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