Results 81 to 90 of about 1,069,040 (297)

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA [PDF]

open access: yes, 2018
Replication Protein A (RPA), the major eukaryotic single stranded DNA-binding protein, binds to exposed ssDNA to protect it from nucleases, participates in a myriad of nucleic acid transactions and coordinates the recruitment of other important players ...
Caldwell, Colleen C.   +16 more
core   +1 more source

Molecular communications in complex systems of dynamic supramolecular polymers [PDF]

open access: yes, 2021
Supramolecular polymers are composed of monomers that self-assemble non-covalently, generating distributions of monodimensional fibres in continuous communication with each other and with the surrounding solution.
Martina, Crippa   +7 more
core   +1 more source

Natural selection and population dynamics [PDF]

open access: yesTrends in Ecology & Evolution, 2006
To what extent, and under which circumstances, are population dynamics influenced by concurrent natural selection? Density dependence and environmental stochasticity are generally expected to subsume any selective modulation of population growth rate, but theoretical considerations point to conditions under which selection can have an appreciable ...
Ilik, Saccheri, Ilkka, Hanski
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

NATURE AND NURTURE: THE COMPLEX INTERPLAY OF GENETIC AND ENVIRONMENTAL INFLUENCES ON HUMAN BEHAVIOR AND DEVELOPMENT [PDF]

open access: yes, 2004
Foreword / Steven E. Hyman -- Preface -- Introduction: Nature and nurture in human behavior and development: a view of the issues / Cynthia García Call, Elaine L. Bearer and Richard M. Lerner -- Ch 1.

core  

Cytocompatible Enzymatic Hydrogelation of Phenylboronic Acid‐Alginate via H2O2‐Triggered Deboronation

open access: yesMacromolecular Materials and Engineering
This study aims to establish a functional hydrogelation system that integrates both dynamic and static properties without the use of additives. Given the increasing demand for biocompatible and mechanically tunable hydrogels, a hydrogelation strategy to ...
Ryota Goto, Shinji Sakai
doaj   +1 more source

Hamiltonian nature of monopole dynamics

open access: yesPhysics Letters A, 2020
Classical electromagnetism with magnetic monopoles is not a Hamiltonian field theory because the Jacobi identity for the Poisson bracket fails. The Jacobi identity is recovered only if all of the species have the same ratio of electric to magnetic charge or if an electron and a monopole can never collide. Without the Jacobi identity, there are no local
J.M. Heninger, P.J. Morrison
openaire   +3 more sources

"Nature And Dynamics Of Work Groups " [PDF]

open access: yesAnnales Universitatis Apulensis Series Oeconomica, 2012
Organizational management has experienced an accelerated evolution in recent years due to changes on the labor market and socio-economic structures. This has resulted in a series of changes at the microeconomic level imposed by the need to adapt to new conditions in order to obtain maximum performance and impact.
Maria Daniela Pipas1, Mohammad Jaradat2
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dynamic hook-and-eye nanoparticle sponges [PDF]

open access: yes, 2009
Systems in which nanoscale components of different types can be captured and/or released from organic scaffolds provide a fertile basis for the construction of dynamic, exchangeable functional materials.
J. Fraser Stoddart   +17 more
core   +1 more source

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