Results 111 to 120 of about 421,141 (266)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Modeling homophily in dynamic networks with application to HIV molecular surveillance. [PDF]

BMC Infect Dis, 2023
DeGruttola V, Nakazawa M, Lin T, Liu J, Goyal R, Little S, Tu X, Mehta S.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Energy and Spectral Efficiency Analysis for UAV-to-UAV Communication in Dynamic Networks for Smart Cities

Smart Cities
Unmanned Aerial Vehicles (UAVs) are integral to the development of smart city infrastructures, enabling essential services such as real-time surveillance, urban traffic regulation, and cooperative environmental monitoring.
Mfonobong Uko, Sunday Ekpo, Ubong Ukommi, Unwana Iwok, Stephen Alabi   +4 more
doaj   +1 more source

Thermally Reversible Organocatalyst for the Accelerated Reprocessing of Dynamic Networks with Creep Resistance. [PDF]

ACS Macro Lett, 2023
Vozzolo G, Ximenis M, Mantione D, Fernández M, Sardon H.   +4 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Attention-Based Anomaly Detection in Dynamic Network

Big Data Mining and Analytics
Detecting anomalies in dynamic networks is essential for a range of real-world applications, such as social networks and cybersecurity. However, it encounters substantial challenges due to the diverse and ever-evolving nature of these anomalies.
Yiming Zhao, Wenjun Wang, Nannan Wu, Jilei Liu, Ying Sun, Wei Yu, Quannan Zu   +6 more
doaj   +1 more source

Dynamic networks of cortico-muscular interactions in sleep and neurodegenerative disorders. [PDF]

Front Netw Physiol, 2023
Rizzo R, Wang JWJL, DePold Hohler A, Holsapple JW, Vaou OE, Ivanov PC.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The amplitude-amplitude cross-frequency coupling method: a step-by-step guide to quantifying physiological network interactions

Frontiers in Network Physiology
The human organism operates as an integrated network in which multiple physiological systems dynamically coordinate across spatial and temporal scales. Quantifying these interactions requires analytical frameworks that move beyond single-system measures ...
Sergi Garcia-Retortillo, Óscar Abenza, Yaopeng J. X. Ma, Plamen Ch. Ivanov, Plamen Ch. Ivanov, Plamen Ch. Ivanov   +5 more
doaj   +1 more source